Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10271926 | 0.79 | KDR (0.35) | PDE4BKDRMAPTL3MBTL1 | |
| SCHEMBL3799229 | 0.68 | KDR (0.41) | KDRDPP4 | |
| SCHEMBL22411485 | 0.68 | KDM4E (0.38) | KDRMAPTL3MBTL1 | |
| SCHEMBL10064935 | 0.67 | TYMS (0.41) | — | |
| SCHEMBL18661712 | 0.65 | DPP4 (0.32) | DPP4 | |
| SCHEMBL1061823 | 0.64 | KDR (0.41) | KDRMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL5133297 | 0.63 | PDE4B (0.49) | PDE4BKDRCDC7 | |
| SCHEMBL1617798 | 0.63 | KDM4E (0.59) | MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL2922186 | 0.63 | KDM4E (0.53) | MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL16916437 | 0.62 | KDM4E (0.32) | MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117425-A1 | CERTAIN SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | BIOGEN IDEC MA INC. (US) | 2010-10-14 | — | — | WO | disclosed |