Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FUCA1 | P04066 | 9/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31274418 | 0.74 | — | — | |
| Pentane SCHEMBL9633320 | 0.73 | TSHR (1.00) | TSHRLMNATHRBALDH1A1TDP1 | |
| Pentane SCHEMBL323650 | 0.73 | TSHR (1.00) | TSHRLMNATHRBALDH1A1TDP1 | |
| Pentane SCHEMBL1234 | 0.73 | — | — | |
| SCHEMBL18025439 | 0.73 | — | — | |
| Pentane SCHEMBL9634178 | 0.73 | TSHR (1.00) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL4781604 | 0.73 | — | — | |
| SCHEMBL598343 | 0.73 | — | — | |
| Pentane SCHEMBL9633144 | 0.73 | TSHR (1.00) | TSHRLMNATHRBALDH1A1TDP1 | |
| SCHEMBL107482 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069916-A | A kind of 2,4- diaryl for preparing phenyl ring ortho position acetoxylation substitutes the method for -1,3,5 pyrrolotriazine derivatives | 中国科学院大连化学物理研究所 | 2018-05-25 | — | — | CN | claimed |
| EP-1123095-A1 | PHARMACEUTICAL FORMULATIONS USEFUL TO TREAT INFLAMMATORY AND IMMUNE DISORDERS | Millennium Pharmaceuticals, Inc. (US) | 2001-08-16 | — | — | EP | claimed |
| WO-2000023071-A9 | PHARMACEUTICAL FORMULATIONS USEFUL TO TREAT INFLAMMATORY AND IMMUNE DISORDERS | LEUKOSITE INC (US) | 2000-09-14 | — | — | WO | claimed |
| WO-2000023071-A1 | PHARMACEUTICAL FORMULATIONS USEFUL TO TREAT INFLAMMATORY AND IMMUNE DISORDERS | LEUKOSITE, INC. (US) | 2000-04-27 | — | — | WO | claimed |
| US-5536874-A | Process for preparing arylacetic acid and arylpropionic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1996-07-16 | — | — | US | claimed |
| US-4597903-A | Process for the direct preparation of N,N-disubstituted derivatives for 4,13-diaza-18-crown-6 | UNIVERSITY OF MARYLAND (US) | 1986-07-01 | — | — | US | claimed |
| US-4329450-A | Nogalamycin analog containing compounds | THE UPJOHN COMPANY (US) | 1982-05-11 | — | — | US | claimed |
| CN-110121497-A | Amidine catalyst for curable compositions | SIKA技术股份公司 | 2019-08-13 | — | — | CN | disclosed |
| CN-105246954-B | Surface modification method of three-dimensional object and injector gasket | 住友橡胶工业株式会社 | 2019-07-12 | — | — | CN | disclosed |
| CN-108239036-A | The process units of polypropylene ultra-violet absorber UV-328 | 成都韦恩斯科技有限公司 | 2018-07-03 | — | — | CN | disclosed |
| CN-108069916-A | A kind of 2,4- diaryl for preparing phenyl ring ortho position acetoxylation substitutes the method for -1,3,5 pyrrolotriazine derivatives | 中国科学院大连化学物理研究所 | 2018-05-25 | — | — | CN | disclosed |
| CN-108069916-A | A kind of 2,4- diaryl for preparing phenyl ring ortho position acetoxylation substitutes the method for -1,3,5 pyrrolotriazine derivatives | 中国科学院大连化学物理研究所 | 2018-05-25 | — | — | CN | disclosed |
| CN-102958930-B | [1,8] naphthyridine compounds as the 2,4- diaryl substitution for the kinase inhibitor to anticancer | 默克专利有限公司 | 2018-04-27 | — | — | CN | disclosed |
| US-4500544-A | ANTIDIABETIC AGENTS; ANTITUMOR AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1985-02-19 | — | — | US | disclosed |
| US-4487923-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1984-12-11 | — | — | US | disclosed |
| EP-0082002-A1 | Method of preparing 23-monoesters of mycaminosyl-tylonolide or demycinosyl-tylosine | ELI LILLY AND COMPANY (US) | 1983-06-22 | — | — | EP | disclosed |
| EP-0074628-A2 | Ascochlorin derivatives; process for preparing the same and pharmaceutical composition containing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1983-03-23 | — | — | EP | disclosed |
| US-4214080-A | Fortimicins AM and AP | ABBOTT LABORATORIES (US) | 1980-07-22 | — | — | US | disclosed |
| US-4166849-A | Peruvoside derivatives and processes for their preparation | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1979-09-04 | — | — | US | disclosed |
| US-4036853-A | ANTIBACTERIAL | PFIZER INC. (US) | 1977-07-19 | — | — | US | disclosed |