Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3799863 | 0.94 | EGLN1 (0.47) | EGLN1 | |
| SCHEMBL3020539 | 0.89 | EGLN1 (0.69) | EGLN1 | |
| SCHEMBL3027014 | 0.87 | EGLN1 (0.65) | EGLN1 | |
| SCHEMBL3026665 | 0.80 | EGLN1 (0.58) | EGLN1 | |
| SCHEMBL3030706 | 0.80 | EGLN1 (0.73) | EGLN1 | |
| SCHEMBL3036766 | 0.79 | EGLN1 (0.59) | EGLN1 | |
| SCHEMBL3025691 | 0.77 | EGLN1 (0.76) | EGLN1 | |
| SCHEMBL3038921 | 0.76 | EGLN1 (0.57) | EGLN1 | |
| SCHEMBL16857818 | 0.76 | EGLN1 (0.50) | EGLN1 | |
| SCHEMBL3025743 | 0.75 | EGLN1 (0.77) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-A1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | Janssen Pharmaceutica, N.V. (BE) | 2011-12-21 | — | — | EP | claimed |
| WO-2010093727-A1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-08-19 | — | — | WO | claimed |