Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.57 |
| ▸ | LCK | P06239 | 7/20 | 0.48 |
| ▸ | JAK3 | P52333 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3801201 | 0.96 | BTK (0.56) | BTKLCKJAK3EGFR | |
| SCHEMBL3726736 | 0.95 | BTK (0.57) | BTKLCKJAK3EGFR | |
| SCHEMBL3313920 | 0.95 | BTK (0.59) | BTKLCKJAK3EGFR | |
| SCHEMBL3797736 | 0.93 | BTK (0.57) | BTKLCKJAK3EGFR | |
| SCHEMBL3316306 | 0.92 | BTK (0.59) | BTKLCKJAK3EGFR | |
| SCHEMBL3316330 | 0.92 | BTK (0.59) | BTKLCKJAK3EGFR | |
| SCHEMBL3409941 | 0.92 | BTK (0.59) | BTKLCKJAK3EGFR | |
| SCHEMBL3314411 | 0.91 | BTK (0.69) | BTKLCKJAK3EGFR | |
| SCHEMBL3798839 | 0.91 | BTK (0.54) | BTKLCKJAK3EGFR | |
| SCHEMBL3795780 | 0.90 | BTK (0.54) | BTKLCKJAK3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068810-A2 | CERTAIN SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF | CGI PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | WO | claimed |
| WO-2010068810-A2 | CERTAIN SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF | CGI PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | WO | disclosed |