Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 18/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL380829 | 0.97 | CHRM2 (0.49) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL381202 | 0.93 | CHRM2 (0.53) | CHRM2CHRM3 | |
| SCHEMBL381175 | 0.91 | CHRM2 (0.52) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL379977 | 0.90 | CHRM3 (0.57) | CHRM2CHRM3 | |
| SCHEMBL381659 | 0.90 | CHRM3 (0.57) | CHRM2CHRM3 | |
| Hydrochloric Acid SCHEMBL380940 | 0.90 | CHRM3 (0.57) | CHRM2CHRM3 | |
| SCHEMBL380842 | 0.90 | CHRM2 (0.58) | CHRM2CHRM3 | |
| SCHEMBL10279210 | 0.88 | CHRM2 (0.60) | CHRM2CHRM3 | |
| SCHEMBL380151 | 0.87 | CHRM3 (0.59) | CHRM2CHRM3 | |
| SCHEMBL783807 | 0.87 | CHRM2 (0.61) | CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476253-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-07-02 | — | — | US | disclosed |
| EP-2409977-A1 | AMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2012-01-25 | — | — | EP | disclosed |