SCHEMBL380330

SCHEMBL380330

CCO[Si](C)(CCCCN(CC)CC)OCC

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 2/20 0.33
HRH3 Q9Y5N1 2/20 0.33
SIGMAR1 Q99720 1/20 0.32
ALDH1A1 P00352 1/20 0.32
SLC2A1 P11166 1/20 0.32
APOBEC3A P31941 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379818 0.94 SLC2A1 (0.32) HRH4HRH3ALDH1A1SLC2A1APOBEC3A
SCHEMBL16813766 0.90 SLC2A1 (0.31) SLC2A1
SCHEMBL16389857 0.89 CHRM2 (0.31)
SCHEMBL16813408 0.86 SLC2A1 (0.31) SLC2A1
SCHEMBL15611804 0.85 KDM4E (0.32) ALDH1A1SLC2A1
SCHEMBL158102 0.85 MEN1 (0.30)
SCHEMBL3595183 0.85
SCHEMBL31687731 0.84 SLC2A1 (0.30) SLC2A1
SCHEMBL31687758 0.84 SLC2A1 (0.30) SLC2A1
SCHEMBL31687744 0.84 SLC2A1 (0.30) SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2511334-B1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE SUMITOMO RUBBER IND (JP) 2018-04-25 EP disclosed
EP-2174801-B1 Rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2016-10-19 EP disclosed
US-8800621-B2 Rubber composition and tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-08-12 US disclosed
US-20120283354-A1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-11-08 US disclosed
EP-2366558-B1 Tire rubber composition and heavy-load tire SUMITOMO RUBBER IND (JP) 2012-10-31 EP disclosed
EP-2511334-A1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE Sumitomo Rubber Industries, Ltd. (JP) 2012-10-17 EP disclosed
EP-2366557-B1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2012-05-23 EP disclosed
US-8163821-B2 Tire rubber composition and heavy-load tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-04-24 US disclosed
EP-2184317-B1 Rubber composition and tire SUMITOMO RUBBER IND (JP) 2012-04-18 EP disclosed
US-8119721-B2 Tread rubber composition for studless tire and studless tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-02-21 US disclosed
US-20110230613-A1 TIRE RUBBER COMPOSITION AND HEAVY-LOAD TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-09-22 US disclosed
US-20110230593-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-09-22 US disclosed
EP-2366557-A1 Tire rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2011-09-21 EP disclosed
EP-2366558-A1 Tire rubber composition and heavy-load tire Sumitomo Rubber Industries, Ltd. (JP) 2011-09-21 EP disclosed
EP-2196324-A1 Tread rubber composition for studless tire and studless tire Sumitomo Rubber Industries, Ltd. (JP) 2010-06-16 EP disclosed
US-20100144954-A1 TREAD RUBBER COMPOSITION FOR STUDLESS TIRE AND STUDLESS TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-06-10 US disclosed
EP-2184317-A1 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-12 EP disclosed
US-20100108213-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-05-06 US disclosed
EP-2174801-A2 Rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2010-04-14 EP disclosed
US-20100084065-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-08 US disclosed