SCHEMBL38045

SCHEMBL38045

[CH]1NCCCS1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL564450 0.91
SCHEMBL2509868 0.88
SCHEMBL2506865 0.88
SCHEMBL285503 0.88
SCHEMBL1829299 0.71
SCHEMBL173784 0.61
SCHEMBL3277375 0.59
SCHEMBL3276475 0.57
SCHEMBL871674 0.57
SCHEMBL18686 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814698-B2 Methods for simultaneous leaching and extraction of precious metals EXCIR WORKS CORP. (CA) 2023-11-14 US claimed
EP-3808749-B1 PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES VERTEX PHARMA (US) 2023-03-08 EP claimed
US-20220340998-A1 METHODS FOR SIMULTANEOUS LEACHING AND EXTRACTION OF PRECIOUS METALS EXCIR WORKS CORP. (CA) 2022-10-27 US claimed
US-11427886-B2 Methods for simultaneous leaching and extraction of precious metals EXCIR WORKS CORP. (CA) 2022-08-30 US claimed
EP-3808749-A1 PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES Vertex Pharmaceuticals Incorporated (US) 2021-04-21 EP claimed
EP-3770148-A1 RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF Beijing Tide Pharmaceutical Co., Ltd. (CN) 2021-01-27 EP claimed
EP-3418281-B1 PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES VERTEX PHARMA (US) 2020-09-30 EP claimed
EP-3418281-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES Vertex Pharmaceuticals Inc. (US) 2018-12-26 EP claimed
US-20180142322-A1 METHODS FOR SIMULTANEOUS LEACHING AND EXTRACTION OF PRECIOUS METALS UNIVERSITY OF SASKATCHEWAN (CA) 2018-05-24 US claimed
US-20180112289-A1 METHODS FOR SELECTIVE LEACHING AND EXTRACTION OF PRECIOUS METALS IN ORGANIC SOLVENTS UNIVERSITY OF SASKATCHEWAN (CA) 2018-04-26 US claimed
WO-2014081689-A1 COMPOUNDS USEFUL AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE VERTEX PHARMACEUTICALS INCORPORATED (US) 2014-05-30 WO claimed
US-7465748-B2 Antiherpesvirus drugs; great pharmacokinetics, good antivirus activity when administered orally at a low dose, high safety profile, less mutagenic concerns; N-(2,6-dimethylphenyl)-N-(2-{[4-(1,3-oxazol-4-yl)phenyl]amino)-2-oxoethyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide ASTELLAS PHARMA INC. (JP) 2008-12-16 US claimed
US-20060229295-A1 Amide derivatives ASTELLAS PHARMA INC.AND RATIONAL DRUG DESIGN (JP) 2006-10-12 US claimed
US-20060211697-A1 2-(2 Or 4-substituted aryloxy)-phenol derivatives as antibacterial agents EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG, INC. 2006-09-21 US claimed
CN-1832930-A Amide derivative YAMANOUCHI PHARMA CO LTD (JP) 2006-09-13 CN claimed
EP-1652843-A1 AMIDE DERIVATIVES Astellas Pharma Inc. (JP) 2006-05-03 EP claimed
US-6358982-B1 FOR THERAPY OF CENTRAL NERVOUS SYSTEM (CNS) DISORDERS ELI LILLY AND COMPANY 2002-03-19 US claimed
EP-1100497-A4 HETEROCYCLYL SULPHONAMIDE DERIVATIVES LILLY CO ELI (US) 2001-09-12 EP claimed
EP-1100497-A1 HETEROCYCLYL SULPHONAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 2001-05-23 EP claimed
WO-2000006158-A1 HETEROCYCLYL SULPHONAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 2000-02-10 WO claimed