Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | ST6GAL1 | P15907 | 9/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL800855 | 0.90 | POLG (0.55) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL13173263 | 0.90 | POLG (0.55) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL800670 | 0.90 | POLG (0.55) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL1274372 | 0.90 | POLG (0.55) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL800406 | 0.90 | POLG (0.55) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL1763223 | 0.88 | NT5E (0.64) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL3789915 | 0.88 | NT5E (0.64) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL3926895 | 0.88 | NT5E (0.61) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL1763085 | 0.88 | NT5E (0.64) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL15045996 | 0.86 | NT5E (0.59) | NT5ELMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408927-A1 | PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010105851-A1 | PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-23 | — | — | WO | disclosed |