⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2765 | 0.67 | — | — | |
| SCHEMBL28124906 | 0.67 | — | — | |
| SCHEMBL31500732 | 0.63 | — | — | |
| Lithium SCHEMBL30434301 | 0.63 | — | — | |
| Hydrogen Sulfide SCHEMBL27930911 | 0.63 | — | — | |
| SCHEMBL1502365 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL28757273 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL4972828 | 0.63 | — | — | |
| Ammonia Solution, Strong SCHEMBL28302802 | 0.63 | — | — | |
| Carbon Dioxide SCHEMBL9347646 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101108809-B | 1- (alkylaminoalkyl-pyrrolidine-/piperidinyl) -2, 2-diphenylacetamide derivatives as muscarinic receptor antagonists | THERAVANCE INC | 2010-07-14 | — | — | CN | claimed |
| EP-2057124-A2 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM, LLC (BM) | 2009-05-13 | — | — | EP | claimed |
| CN-101277961-A | Tetrahydropyrrolizinone compounds as LFA-1 modulators | NOVARTIS AG (CH) | 2008-10-01 | — | — | CN | claimed |
| CN-100404544-C | 9-ketospinosyn derivatives | BAYER CROPSCIENCE AG (DE) | 2008-07-23 | — | — | CN | claimed |
| WO-2008011611-A2 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2008-01-24 | — | — | WO | claimed |
| CN-101108809-A | 1- (alkylaminoalkyl-pyrrolidine-/piperidinyl) -2, 2-diphenylacetamide derivatives as muscarinic receptor antagonists | THERAVANCE INC (US) | 2008-01-23 | — | — | CN | claimed |
| US-20070135499-A1 | Hydrazide compounds | AERIE PHARMACEUTICALS, INC. (US) | 2007-06-14 | — | — | US | claimed |
| WO-2007008942-A2 | PHENYLAMINO-ACETIC ACID [1-(PYRIDIN-4-YL)-METHYLIDENE]-HYDRAZIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF G PROTEIN-COUPLED RECEPTOR KINASES FOR THE TREATMENT OF EYE DISEASES | AERIE PHARMACEUTICALS, INC. (US) | 2007-01-18 | — | — | WO | claimed |
| CN-1805927-A | 1- (alkylaminoalkyl-pyrrolidine-/piperidinyl) -2, 2-diphenylacetamide derivatives as muscarinic receptor antagonists | THERAVANCE INC (US) | 2006-07-19 | — | — | CN | claimed |
| CN-1784416-A | 9-ketospinosyn derivatives | BAYER CROPSCIENCE AG (DE) | 2006-06-07 | — | — | CN | claimed |
| EP-1590358-A1 | 9-KETOSPINOSYN DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2005-11-02 | — | — | EP | claimed |
| WO-2004065402-A1 | 9-KETOSPINOSYN DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-08-05 | — | — | WO | claimed |
| EP-0135249-B1 | STYRENE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1986-11-12 | — | — | EP | claimed |
| CN-105814051-A | Tetrahydroimidazopyridine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-105814065-A | Imidazothiazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-103080080-B | 6,7-dihydro-5H-benzo [7] takes turns ene derivative, its preparation method, the pharmaceutical preparation comprising it and its purposes for the preparation of medicine | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-26 | — | — | CN | disclosed |
| EP-0374097-A2 | Use of peptide isosteres as retroviral protease inhibitors | CIBA-GEIGY AG (CH) | 1990-06-20 | — | — | EP | disclosed |
| EP-0374098-A2 | Inhibitors of retroviral proteases | CIBA-GEIGY AG (CH) | 1990-06-20 | — | — | EP | disclosed |
| EP-0347146-A2 | Fused pyrimidine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-12-20 | — | — | EP | disclosed |
| EP-0287951-A2 | 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-26 | — | — | EP | disclosed |