Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50111 | 0.98 | FOLH1 (0.57) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL43620 | 0.98 | FOLH1 (0.57) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL28109489 | 0.96 | FOLH1 (0.56) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| Water SCHEMBL28073715 | 0.96 | FOLH1 (0.56) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| Water SCHEMBL380638 | 0.96 | FOLH1 (0.56) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL901403 | 0.96 | FOLH1 (0.56) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL11155336 | 0.92 | FOLH1 (0.50) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL11148798 | 0.92 | FOLH1 (0.50) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| SCHEMBL28165413 | 0.92 | FOLH1 (0.50) | FOLH1GSRRNPEPSLC6A5MMP2 | |
| Trifluoroacetic Acid SCHEMBL28362804 | 0.89 | FOLH1 (0.49) | FOLH1GSRRNPEPSLC6A5MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408927-A1 | PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2012-01-25 | — | — | EP | disclosed |