Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17500721 | 0.76 | CA1 (0.30) | CA1CA2 | |
| SCHEMBL4545251 | 0.71 | — | — | |
| SCHEMBL777670 | 0.70 | CA1 (0.39) | CA1CA2 | |
| SCHEMBL12095289 | 0.69 | — | — | |
| SCHEMBL4545253 | 0.64 | KDM4E (0.37) | CA1CA2 | |
| SCHEMBL28128349 | 0.64 | — | — | |
| SCHEMBL28654753 | 0.63 | CA1 (0.32) | CA1CA2 | |
| SCHEMBL8397879 | 0.61 | CA1 (0.39) | CA1CA2 | |
| Sulfuric Acid Diethyl Ester SCHEMBL10897517 | 0.60 | CA1 (0.48) | CA1CA2 | |
| SCHEMBL8398627 | 0.60 | CA1 (0.37) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10966980-B2 | Pyrrolo[2,3-d]pyrimidine derivatives | PFIZER INC. (US) | 2021-04-06 | — | — | US | disclosed |
| EP-3180344-B1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES USEFUL FOR INHIBITING JANUS KINASE | PFIZER (US) | 2019-09-18 | — | — | EP | disclosed |
| EP-3180344-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES USEFUL FOR INHIBITING JANUS KINASE | Pfizer Inc (US) | 2017-06-21 | — | — | EP | disclosed |
| US-20160045508-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES | PFIZER INC. (US) | 2016-02-18 | — | — | US | disclosed |
| WO-2016024185-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES USEFUL FOR INHIBITING JANUS KINASE | PFIZER INC. (US) | 2016-02-18 | — | — | WO | disclosed |
| WO-2010145197-A1 | NOVEL 6-ARYLAMINO PYRIDONE SULFONAMIDES AND 6-ARYLAMINO PYRAZINONE SULFONAMDIES AS MEK INHIBITORS | CHEMIZON (BEIJING), LTD. (CN) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160045508-A1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES | JAK3, JAK1, JAK2 | CA1 4869/4885CA2 4114/4885 |
| US-10966980-B2 | Pyrrolo[2,3-d]pyrimidine derivatives | JAK3, JAK1, JAK2 | CA1 4869/4885CA2 4114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.