SCHEMBL380862

SCHEMBL380862

C=COOOOOCCCCCCCCCCCCCCCC

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.37
LPAR1 Q92633 3/20 0.33
LPAR3 Q9UBY5 3/20 0.33
LPAR2 Q9HBW0 2/20 0.33
THRB P10828 2/20 0.32
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPT P10636 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2418215 1.00 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL15350859 1.00 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL15351768 1.00 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL15351783 1.00 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL9442715 1.00 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL5265569 1.00 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL15350980 1.00 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL15351711 1.00 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL10524053 1.00 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB
SCHEMBL15350621 1.00 TSHR (0.37) TSHRLPAR1LPAR3LPAR2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1862478-B1 POLYMER PARTICLE, RESIN COMPOSITION CONTAINING SAME, AND MOLDED BODY MITSUBISHI RAYON CO (JP) 2012-01-25 EP disclosed
EP-1862478-A1 POLYMER PARTICLE, RESIN COMPOSITION CONTAINING SAME, AND MOLDED BODY Mitsubishi Rayon Co., Ltd. (JP) 2007-12-05 EP disclosed