SCHEMBL381074

SCHEMBL381074

OCc1cncc(Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30296134 1.00
Hydrochloric Acid SCHEMBL4422238 0.98 POLB (0.42)
Hydrochloric Acid SCHEMBL3163389 0.98 POLB (0.42)
SCHEMBL3720583 0.96 POLB (0.41)
SCHEMBL28089087 0.87 KDM4E (0.42)
SCHEMBL783406 0.82 POLB (0.41)
SCHEMBL22770930 0.82
SCHEMBL2728918 0.82 CYP2A6 (0.47)
SCHEMBL3183730 0.78
SCHEMBL1502528 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116891606-B Antibacterial and antifogging master batch for polypropylene film and preparation method thereof 汕头市贝斯特科技有限公司 2023-12-12 CN claimed
CN-116891606-A Antibacterial and antifogging master batch for polypropylene film and preparation method thereof 汕头市贝斯特科技有限公司 2023-10-17 CN claimed
CN-114716363-B Novel hydroxyl-containing pyridine quaternary ammonium salt compound, synthesis method thereof and application thereof in antibacterial modification of fibers 河南驼人医疗器械研究院有限公司 2023-06-16 CN claimed
CN-116120226-A Synthesis process of 5-hydroxymethyl nicotinonitrile 湖南阿斯迪康药业有限公司 2023-05-16 CN claimed
CN-114716363-A Novel pyridine quaternary ammonium salt compound containing hydroxyl, synthetic method thereof and application thereof in fiber antibacterial modification 河南驼人医疗器械研究院有限公司 2022-07-08 CN claimed
EP-4565562-B1 PYRROLIDINE-2-CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES NXERA PHARMA UK LTD (GB) 2026-05-27 EP disclosed
US-20260116878-A1 INDAZOLE INHIBITORS OF THE WNT SIGNAL PATHWAY AND THERAPEUTIC USES THEREOF BIOSPLICE THERAPEUTICS INC (US) 2026-04-30 US disclosed
EP-4073062-B1 FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) RYVU THERAPEUTICS S A (PL) 2026-04-29 EP disclosed
US-20260042745-A1 PYRROLIDINE-2-CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES NXERA PHARMA UK LIMITED (GB) 2026-02-12 US disclosed
US-12545689-B2 Macrocyclic LRRK2 kinase inhibitors ONCODESIGN PRECISION MEDICINE (FR) 2026-02-10 US disclosed
US-12509424-B2 Compound and composition as PDGF receptor kinase inhibitor NIPPON SHINYAKU CO., LTD. (JP) 2025-12-30 US disclosed
US-12492174-B2 Morpholine-3-carboxamide derivatives as prostaglandin E2 receptor 4 (EP4) agonists for the treatment of gastrointestinal and pulmonary diseases NXERA PHARMA UK LIMITED (GB) 2025-12-09 US disclosed
US-5191084-A PHENYL PYRAZOLIDINONES AS BRONCHODILATORS AND ANTI-INFLAMMATORY AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1993-03-02 US disclosed
US-5175301-A Insecticide, miticide, pesticide TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-29 US disclosed
EP-0511865-A1 Phenyl pyrazolidinones as bronchodilators and anti-inflammatory agents AMERICAN HOME PRODUCTS CORPORATION (US) 1992-11-04 EP disclosed
EP-0509559-A2 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-21 EP disclosed
EP-0486948-A2 Retroviral protease inhibiting compounds ABBOTT LABORATORIES (US) 1992-05-27 EP disclosed
US-5002949-A Anticoagulants AMERICAN HOME PRODUCTS CORPORATION (US) 1991-03-26 US disclosed
EP-0302389-A2 Alpha-unsaturated amines, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-02-08 EP disclosed
US-4732977-A BACTERICIDES BRISTOL MYERS COMPANY (US) 1988-03-22 US disclosed