Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 16/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 16/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16566459 | 0.76 | HDAC6 (0.41) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL18356434 | 0.67 | HDAC1 (0.41) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL4306176 | 0.67 | HDAC3 (0.40) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL2143881 | 0.67 | HDAC3 (0.40) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL16580910 | 0.66 | HDAC1 (0.49) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL16566468 | 0.66 | HDAC1 (0.50) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL1365287 | 0.66 | HDAC1 (0.50) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL8009252 | 0.66 | HDAC1 (0.50) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL15832598 | 0.65 | CHRNA7 (0.56) | HDAC1HDAC6HDAC3HDAC2HDAC4 | |
| SCHEMBL15832596 | 0.65 | CHRNA7 (0.56) | HDAC1HDAC6HDAC3HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137462-A2 | METHODS FOR TREATING COGNITIVE DISORDERS USING INHIBITORS OF HISTONE DEACETYLASE | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | claimed |