SCHEMBL3811067

SCHEMBL3811067

CCCC(=O)c1ccc(O)c(OC)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.64
SLC22A8 Q8TCC7 1/20 0.64
MEN1 O00255 1/20 0.64
RAB9A P51151 1/20 0.64
KMT2A Q03164 1/20 0.64
KDM4E B2RXH2 1/20 0.63
POLB P06746 1/20 0.63
HSD17B2 P37059 1/20 0.62
HTT P42858 1/20 0.62
CYP1A2 P05177 1/20 0.60
HSP90AA1 P07900 1/20 0.60
HSP90AB1 P08238 1/20 0.60
BLM P54132 1/20 0.60
HDAC6 Q9UBN7 1/20 0.55
ALOX5 P09917 1/20 0.55
NFKB1 P19838 1/20 0.55
STAT3 P40763 1/20 0.55
NFKB2 Q00653 1/20 0.55
RELA Q04206 1/20 0.55
PDE4D Q08499 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30266750 1.00 SLC22A6 (0.64) SLC22A6SLC22A8MEN1RAB9AKMT2A
SCHEMBL29084362 0.91 HTT (0.56) SLC22A6SLC22A8MEN1RAB9AKMT2A
SCHEMBL26141260 0.90 KDM4E (0.60) SLC22A6SLC22A8MEN1RAB9AKMT2A
SCHEMBL22390229 0.89 CYP1A2 (0.59) SLC22A6SLC22A8MEN1RAB9AKMT2A
SCHEMBL28541651 0.88 CYP1A2 (0.61) SLC22A6SLC22A8MEN1RAB9AKMT2A
SCHEMBL20476155 0.88 CYP1A2 (0.61) SLC22A6SLC22A8MEN1RAB9AKMT2A
SCHEMBL29595420 0.87 SLC22A6 (0.64) SLC22A6SLC22A8MEN1RAB9AKMT2A
SCHEMBL4545341 0.87 SLC22A6 (0.64) SLC22A6SLC22A8MEN1RAB9AKMT2A
Oxalic Acid SCHEMBL28535857 0.86 HTT (0.58) SLC22A6SLC22A8MEN1RAB9AKMT2A
SCHEMBL1396833 0.86 MEN1 (0.68) SLC22A6SLC22A8MEN1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118341458-A Lignin depolymerization catalyst and preparation method and application thereof 北华大学 2024-07-16 CN claimed
CN-118341458-A Lignin depolymerization catalyst and preparation method and application thereof 北华大学 2024-07-16 CN disclosed
CN-118341458-A Lignin depolymerization catalyst and preparation method and application thereof 北华大学 2024-07-16 CN disclosed
WO-2021058483-A1 PROCESS FOR PRODUCING LIGNIN COMPONENTS FROM LIGNOCELLULOSIC BIOMASS Université Catholique de Louvain (BE) 2021-04-01 WO disclosed
CN-110643428-A Lemon and vanilla compound aroma type perfume essence and application thereof 武汉黄鹤楼香精香料有限公司 2020-01-03 CN disclosed
CN-107735254-A Absorbing sheet 王子控股株式会社 2018-02-23 CN disclosed
CN-105831802-B One kind is used for agilawood cigarette overlapping glue agalloch eaglewood essence and its preparation method and application 湖北中烟工业有限责任公司 2017-06-16 CN disclosed
EP-1951217-A4 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORP (US) 2009-08-12 EP disclosed
US-20090082721-A1 Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction RESPIRATORY DIAGNOSTICS, INC. 2009-03-26 US disclosed
CN-100457255-C Oxygen absorber composition TAKASAGO PERFUMERY CO LTD (JP) 2009-02-04 CN disclosed
US-5276027-A Thiadiazinones MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-01-04 US disclosed
US-5236952-A Inhibit the enzyme catechol-O-methyltransferase; for treatment of Parkinson's disease administered with L-dopa HOFFMANN-LA ROCHE INC. (US) 1993-08-17 US disclosed
EP-0237929-B1 3,5-DISUBSTITUTED PYROCATECHOL DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1993-06-02 EP disclosed
EP-0539806-A1 Thiadiazinones and medicines containing them, having in particular a positive inotropic and vasodilating activity MERCK PATENT GmbH (DE) 1993-05-05 EP disclosed
EP-0237929-A1 3,5-Disubstituted pyrocatechol derivatives F. HOFFMANN-LA ROCHE AG (CH) 1987-09-23 EP disclosed
EP-0028473-B1 CHLORO- AND ALKOXY-SUBSTITUTED-2,4-DIAMINOQUINAZOLINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PFIZER INC. (US) 1985-01-09 EP disclosed
US-4377581-A ANTIHYPERTENSIVE AGENTS PFIZER INC. (US) 1983-03-22 US disclosed
US-4351940-A Chloro- and alkoxy-substituted-2-chloro-4-aminodquinazolines PFIZER INC. (US) 1982-09-28 US disclosed
US-4287341-A USEFUL AS ANTIHYPERTENSIVE AGENTS PFIZER INC. (US) 1981-09-01 US disclosed
EP-0028473-A1 Chloro- and alkoxy-substituted-2,4-diaminoquinazolines and pharmaceutical compositions containing them PFIZER INC. (US) 1981-05-13 EP disclosed