⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29244250 | 0.88 | TP53 (0.30) | — | |
| SCHEMBL9752905 | 0.76 | — | — | |
| SCHEMBL8539535 | 0.74 | — | — | |
| SCHEMBL27945 | 0.74 | — | — | |
| SCHEMBL1990544 | 0.70 | — | — | |
| SCHEMBL816839 | 0.70 | — | — | |
| SCHEMBL1991391 | 0.70 | — | — | |
| SCHEMBL16097487 | 0.70 | — | — | |
| SCHEMBL16097873 | 0.70 | — | — | |
| SCHEMBL345700 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3341 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743434-A1 | CATALYSTS AND METHODS FOR CONVERSION OF 1,1,2-TRICHLORO-1,2,2-TRIFLUOROETHANE (CFC-113) TO 1,1,2-TRIFLUOROETHANE (HFC-143) | Solstice Advanced Materials US Inc. (US) | 2026-05-20 | — | — | EP | claimed |
| US-20260125589-A1 | COMPOSITION CONTAINING TRANS-1,2-DIFLUOROETHYLENE | DAIKIN INDUSTRIES, LTD. (JP) | 2026-05-07 | — | — | US | claimed |
| US-20260062365-A1 | METHOD FOR PRODUCING trans-1,2-DIFLUOROETHYLENE (HFO-1132E) | SOLSTICE ADVANCED MATERIALS US, INC. | 2026-03-05 | — | — | US | claimed |
| EP-4688710-A1 | METHOD FOR PRODUCING TRANS-1,2-DIFLUOROETHYLENE (HFO-1132E) | HONEYWELL INTERNATIONAL INC. (US) | 2026-02-11 | — | — | EP | claimed |
| EP-4683977-A1 | AZEOTROPE AND AZEOTROPE-LIKE COMPOSITIONS OF 1-CHLORO-1,2-DIFLUOROETHANE (HCFC-142A) AND 1,1,2-TRICHLORO-1,2,2-TRIFLUOROETHANE (CFC-113) AND APPLICATIONS THEREOF | Solstice Advanced Materials US, Inc. (US) | 2026-01-28 | — | — | EP | claimed |
| EP-4683901-A1 | AZEOTROPE AND AZEOTROPE-LIKE COMPOSITIONS OF 1-CHLORO-1,2-DIFLUOROETHANE (HCFC-142A) AND 1,2-DICHLORO-1,1,2-TRIFLUOROETHANE (HCFC-123A) AND APPLICATIONS THEREOF | HONEYWELL INTERNATIONAL INC. (US) | 2026-01-28 | — | — | EP | claimed |
| WO-2025264601-A2 | SYSTEMS AND PROCESSES FOR RECOVERY AND RECLAMATION OF THERMAL MANAGEMENT FLUIDS | THE CHEMOURS COMPANY FC, LLC (US) | 2025-12-26 | — | — | WO | claimed |
| US-20250206689-A1 | CATALYST CONDITIONING AND REACTANT DILUTION METHODS IN PROCESSES FOR PRODUCING trans-1,2-DIFLUOROETHYLENE (HFO-1132E) | SOLSTICE ADVANCED MATERIALS US, INC. | 2025-06-26 | — | — | US | claimed |
| WO-2025137535-A1 | CATALYST CONDITIONING AND REACTANT DILUTION METHODS IN PROCESSES FOR PRODUCING TRANS-1,2-DIFLUOROETHYLENE (HFO-1132E) | HONEYWELL INTERNATIONAL INC. (US) | 2025-06-26 | — | — | WO | claimed |
| CN-119977813-A | Preparation method of difluoroethylamine | 宁夏滨河泽瑞新材料科技有限公司 | 2025-05-13 | — | — | CN | claimed |
| US-4515695-A | Extraction of substances from aqueous solution | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-05-07 | — | — | US | claimed |
| US-4510064-A | DICHLORODIFLUOROMETHANE, CHLORODIFLUOROMETHANE CHLORODIFLUOROETHAN, AZEOTROPES | Stevens, Robert D. (US) | 1985-04-09 | — | — | US | claimed |
| EP-0062516-A1 | Composition for absorption refrigeration | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1982-10-13 | — | — | EP | claimed |
| US-4317888-A | MIXING WITH SILICA MICROSPHERES, BLOWING AGENT | ASAHI-DOW LIMITED (JP) | 1982-03-02 | — | — | US | claimed |
| US-4308352-A | Process of extruding polysulfone foam | PACKAGING INDUSTRIES GROUP, INC. (US) | 1981-12-29 | — | — | US | claimed |
| US-4192822-A | Process for producing halogenated hydrocarbons | ALLIED CHEMICAL CORPORATION (US) | 1980-03-11 | — | — | US | claimed |
| EP-0001675-A2 | Process for increasing fuel yield of coal liquefaction | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-05-02 | — | — | EP | claimed |
| EP-0001676-A2 | A process for separating tar and solids from coal liquefaction products | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-05-02 | — | — | EP | claimed |
| US-4148716-A | SYNTHETIC, LOW SULFUR FUELS | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-04-10 | — | — | US | claimed |
| US-4133740-A | Process for increasing the fuel yield of coal liquefaction products by extraction of asphaltenes, resins and aromatic compounds from said coal liquefaction products | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-01-09 | — | — | US | claimed |