SCHEMBL3812751

SCHEMBL3812751

O=C(O)C1C=CCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3153890 0.76
SCHEMBL297777 0.76
SCHEMBL1021492 0.76
Hydrochloric Acid SCHEMBL17841913 0.74
Hydrochloric Acid SCHEMBL17979364 0.74
SCHEMBL7178272 0.73
SCHEMBL14632399 0.68
SCHEMBL4872602 0.67 CYP2D6 (0.37)
SCHEMBL16963142 0.67 EGLN1 (0.72)
SCHEMBL13176095 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0078191-B1 COLLAGEN INHIBITING COMPOSITIONS AND PROCESSES FOR MANUFACTURING AND USING THE SAME UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 1986-09-03 EP claimed
US-4428939-A POLYMERIC HYDROXYPROLINE FOR REDUCTION OF SCAR TISSUE COLLEGE OF MEDICINE AND DENTISTRY OF NEW JERSEY 1984-01-31 US claimed
EP-0078191-A2 Collagen inhibiting compositions and processes for manufacturing and using the same UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 1983-05-04 EP claimed
WO-2024259241-A1 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF Transneural Therapeutics, Inc. (US) 2024-12-19 WO disclosed
WO-2023217230-A1 KINESIN KIF18A INHIBITOR AND USE THEREOF 上海湃隆生物科技有限公司 2023-11-16 WO disclosed
CN-104364254-B Heterobicyclic compounds as beta-lactamase inhibitors 恩塔西斯治疗有限公司 2017-02-22 CN disclosed
CN-104364254-A Heterobicyclic compounds as beta-lactamase inhibitors ASTRAZENECA SWEDEN AB 2015-02-18 CN disclosed
EP-1708704-A4 4-ARYL PIPERIDINES LUNDBECK & CO AS H (DK) 2009-08-05 EP disclosed
EP-1708704-A2 4-ARYL PIPERIDINES H.Lundbeck A/S (DK) 2006-10-11 EP disclosed
WO-2005069834-A2 4-ARYL PIPERIDINES H. LUNDBECK A/S (DK) 2005-08-04 WO disclosed
US-5720950-A ALKOXYLATED PROLINE ANALOG UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY (US) 1998-02-24 US disclosed
EP-0681472-A1 STARCH STABILIZED O-SUBSTITUTED TETRAHYDROPYRIDINE OXIME CHOLINERGIC AGENTS WARNER-LAMBERT COMPANY (US) 1995-11-15 EP disclosed
US-5424301-A Cognition activators WARNER-LAMBERT COMPANY (US) 1995-06-13 US disclosed
US-5372807-A Proline analogs administered to inhibit collagen accumulation UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 1994-12-13 US disclosed
WO-1994017802-A1 STARCH STABILIZED O-SUBSTITUTED TETRAHYDROPYRIDINE OXIME CHOLINERGIC AGENTS WARNER-LAMBERT COMPANY (US) 1994-08-18 WO disclosed
US-4672031-A POLYMERIC FORMS OF CIS-4-HYDROXY PROLINE; REDUCING SCAR TISSUE UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 1987-06-09 US disclosed
US-4625016-A 4-HYDROXYPROLINE POLYESTERS AND POLYPEPTIDES UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 1986-11-25 US disclosed
EP-0078191-B1 COLLAGEN INHIBITING COMPOSITIONS AND PROCESSES FOR MANUFACTURING AND USING THE SAME UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 1986-09-03 EP disclosed
US-4428939-A POLYMERIC HYDROXYPROLINE FOR REDUCTION OF SCAR TISSUE COLLEGE OF MEDICINE AND DENTISTRY OF NEW JERSEY 1984-01-31 US disclosed
EP-0078191-A2 Collagen inhibiting compositions and processes for manufacturing and using the same UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 1983-05-04 EP disclosed