Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 6/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541400 | 0.86 | CALML3 (0.47) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL541401 | 0.86 | CALML3 (0.47) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL541806 | 0.82 | CALML3 (0.59) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL541807 | 0.82 | CALML3 (0.59) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL541126 | 0.80 | CALML3 (0.47) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL541127 | 0.80 | CALML3 (0.47) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL1424121 | 0.80 | CALML3 (0.46) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL709605 | 0.80 | CALML3 (0.46) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL709604 | 0.80 | CALML3 (0.46) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL6398041 | 0.78 | CALML3 (0.49) | CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086968-A1 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008056335-A1 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-05-15 | — | — | WO | disclosed |