Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3
The experimentally established mechanism targets of Epinephrine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 7/20 | 1.00 |
| ▸ | ADRB1 known ✓ | P08588 | 6/20 | 1.00 |
| ▸ | ADRB3 known ✓ | P13945 | 5/20 | 1.00 |
| ▸ | ADRA2A known ✓ | P08913 | 3/20 | 1.00 |
| ▸ | ADRA2B known ✓ | P18089 | 3/20 | 1.00 |
| ▸ | ADRA2C known ✓ | P18825 | 3/20 | 1.00 |
| ▸ | ADRA1A known ✓ | P35348 | 3/20 | 1.00 |
| ▸ | ADRA1B known ✓ | P35368 | 3/20 | 1.00 |
| ▸ | ADRA1D known ✓ | P25100 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 1.00 |
| ▸ | TSHR | P16473 | 5/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | MTOR | P42345 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Racepinephrine SCHEMBL29396039 | 1.00 | KDM4E (1.00) | KDM4ETDP1ADRB2HIF1AMAPT | |
| Racepinephrine SCHEMBL3815 | 1.00 | KDM4E (1.00) | KDM4ETDP1ADRB2HIF1AMAPT | |
| Epinephrine SCHEMBL29353423 | 1.00 | KDM4E (1.00) | KDM4ETDP1ADRB2HIF1AMAPT | |
| [11C]Epinephrine SCHEMBL29374823 | 1.00 | KDM4E (1.00) | KDM4ETDP1ADRB2HIF1AMAPT | |
| L-Adrenaline SCHEMBL11647 | 1.00 | KDM4E (1.00) | KDM4ETDP1ADRB2HIF1AMAPT | |
| Epinephrine SCHEMBL2837188 | 1.00 | KDM4E (1.00) | KDM4ETDP1ADRB2HIF1AMAPT | |
| [11C]Epinephrine SCHEMBL29371663 | 1.00 | KDM4E (1.00) | KDM4ETDP1ADRB2HIF1AMAPT | |
| L-Adrenaline SCHEMBL29519331 | 1.00 | KDM4E (1.00) | KDM4ETDP1ADRB2HIF1AMAPT | |
| Racepinephrine SCHEMBL11631789 | 1.00 | KDM4E (1.00) | KDM4ETDP1ADRB2HIF1AMAPT | |
| Racepinephrine SCHEMBL20493843 | 1.00 | KDM4E (1.00) | KDM4ETDP1ADRB2HIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 347467 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6393320-B1 | — | — | None | — | — | US | claimed |
| US-12184803-B2 | Unmanned aerial vehicle emergency dispatch and diagnostics data apparatus, systems and methods | RAPIDSOS, INC. (US) | 2024-12-31 | — | — | US | claimed |
| US-20240424199-A1 | INTELLIGENT BRACELET CAPABLE OF INJECTING MEDICATIONS | WANG ZIMU (CN) | 2024-12-26 | — | — | US | claimed |
| EP-4475887-A1 | METHODS OF TREATING COMPLEX REGIONAL PAIN SYNDROME | Aisa Pharma, Inc. (US) | 2024-12-18 | — | — | EP | claimed |
| WO-2024251910-A1 | ANTI-ALLERGEN ANTIBODIES AND USES THEREOF | MABYLON AG (CH) | 2024-12-12 | — | — | WO | claimed |
| CN-119072270-A | Solid state sensor for touch-based rapid physiological and chemical sensing | 加利福尼亚大学董事会 | 2024-12-03 | — | — | CN | claimed |
| WO-2024240216-A1 | PHARMACEUTICAL COMPOSITION FOR EFFECTIVELY DELAYING AND TREATING MYOPIA | 温州医科大学附属眼视光医院 | 2024-11-28 | — | — | WO | claimed |
| US-20240390364-A1 | Novel Pyridine Compositions and their use in methods for preventing or treating diseases, disorders and conditions | REID CHRISTOPHER BRIAN (US) | 2024-11-28 | — | — | US | claimed |
| CN-119032272-A | Localized surface plasmon resonance detector | 英国NIVD有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-119013010-A | Inhalable or ingestible lactic acid composition for the treatment of chronic lung disease | 艾维尔勒斯生物公司 | 2024-11-22 | — | — | CN | claimed |
| US-3988339-A | 7 OR 8-SUBSTITUTED 1,2,3,4-TETRAHYDRO-ISOQUINOLINE | SMITHKLINE CORPORATION (US) | 1976-10-26 | — | — | US | claimed |
| US-3981398-A | Aid in the management of clinical emergencies in medical and dental practices and other circumstances | Pienaar, Hendrik Lukas (ZA) | 1976-09-21 | — | — | US | claimed |
| US-3981303-A | Bioerodible ocular device | ALZA CORPORATION (US) | 1976-09-21 | — | — | US | claimed |
| US-3977404-A | OSMOTIC DEVICE HAVING MICROPOROUS RESERVOIR | ALZA CORPORATION (US) | 1976-08-31 | — | — | US | claimed |
| US-3968201-A | POLYMER | PHARMACIA AKTIEBOLAG (SW) | 1976-07-06 | — | — | US | claimed |
| US-3968245-A | Sympathomimetic topical and percutaneous administration with halogenated promoters | ALZA CORPORATION (US) | 1976-07-06 | — | — | US | claimed |
| US-3966905-A | POLYVINYL PYRROLIDONE | BARNES-HIND PHARMACEUTICALS, INC. (US) | 1976-06-29 | — | — | US | claimed |
| US-3962414-A | Structured bioerodible drug delivery device | ALZA CORPORATION (US) | 1976-06-08 | — | — | US | claimed |
| US-3960150-A | Bioerodible ocular device | ALZA CORPORATION (US) | 1976-06-01 | — | — | US | claimed |
| US-3944671-A | ALPHA-(4-AMINOPHENYL)-ALPHA-LOWER ALKYL GLUTARIMIDES OR SALTS | CIBA-GEIGY CORPORATION (US) | 1976-03-16 | — | — | US | claimed |