Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070057 | 0.82 | HTR2A (0.44) | HTR2AHTR2CSLC6A2SLC6A4CDK4 | |
| SCHEMBL598296 | 0.79 | SLC6A2 (0.47) | SLC6A2SLC6A4CDK4CCND1NOTUM | |
| SCHEMBL29591657 | 0.79 | SLC6A2 (0.47) | SLC6A2SLC6A4CDK4CCND1NOTUM | |
| Fluoride SCHEMBL28094988 | 0.78 | SLC6A2 (0.46) | SLC6A2SLC6A4CDK4CCND1NOTUM | |
| SCHEMBL31517709 | 0.78 | SLC6A2 (0.46) | SLC6A2SLC6A4CDK4CCND1NOTUM | |
| SCHEMBL24663442 | 0.76 | SLC6A4 (0.46) | HTR2ASLC6A2SLC6A4CDK4CCND1 | |
| SCHEMBL30460003 | 0.76 | SLC6A4 (0.50) | SLC6A2SLC6A4NOTUM | |
| SCHEMBL17818472 | 0.76 | SLC6A4 (0.46) | SLC6A2SLC6A4CDK4CCND1NOTUM | |
| SCHEMBL10920221 | 0.76 | SLC6A2 (0.45) | SLC6A2SLC6A4CDK4CCND1NOTUM | |
| SCHEMBL1841921 | 0.76 | SLC6A4 (0.50) | SLC6A2SLC6A4NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144517-A1 | PROCESS FOR THE PREPARATION OF CYCLOHEXANOL DERIVATIVES | EGIS GYÓGYSZERGYÁR NYILVÁNOSAN MÜKÖDÖ (HU) | 2009-12-03 | — | — | WO | disclosed |
| US-5721267-A | ANTICANCER AGENTS | SYNTEX (U.S.A.) INC. (US) | 1998-02-24 | — | — | US | disclosed |