Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.57 |
| ▸ | CFTR | P13569 | 2/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831734 | 0.88 | SLC22A6 (0.72) | SLC22A6CFTRNR4A2PBRM1GPR84 | |
| SCHEMBL20481507 | 0.81 | SLC22A6 (0.55) | SLC22A6CFTRPBRM1GABRA1GABRB2 | |
| SCHEMBL8126388 | 0.78 | KDM4E (0.67) | GPR84ALDH1A1KDM4EMPOTSHR | |
| SCHEMBL29551347 | 0.77 | CFTR (0.67) | CFTRNR4A2PBRM1GABRA1GABRB2 | |
| SCHEMBL3653476 | 0.77 | ABCG2 (0.54) | SLC22A6NR4A2PBRM1SMN1; SMN2CREBBP | |
| SCHEMBL377150 | 0.77 | CFTR (0.67) | CFTRNR4A2PBRM1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL9046989 | 0.76 | CFTR (0.65) | CFTRNR4A2PBRM1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL30585295 | 0.76 | CFTR (0.65) | CFTRNR4A2PBRM1GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL29766716 | 0.76 | CFTR (0.65) | CFTRNR4A2PBRM1GABRA1GABRB2 | |
| SCHEMBL2931679 | 0.76 | PBRM1 (0.77) | SLC22A6CFTRNR4A2PBRM1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131839-B1 | QUINOLINE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 1989-02-01 | — | — | EP | claimed |
| EP-2086976-A1 | METHOD FOR PRODUCING PRADOFLOXACIN | Bayer Animal Health GmbH (DE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008046532-A1 | METHOD FOR PRODUCING PRADOFLOXACIN | BAYER ANIMAL HEALTH GMBH (DE) | 2008-04-24 | — | — | WO | disclosed |
| EP-0610958-B1 | Intermediates in the preparation of 4-oxoquinoline-3-carboxylic acid derivatives | UBE INDUSTRIES (JP) | 2001-10-04 | — | — | EP | disclosed |
| EP-0907648-A1 | QUINOLONE CARBOXYLIC ACIDS SUBSTITUTED BY 7-(3-VINYL-1,4-PIPERAZINE-1-YL) | BAYER AG (DE) | 1999-04-14 | — | — | EP | disclosed |
| WO-1998000421-A1 | QUINOLONE CARBOXYLIC ACIDS SUBSTITUTED BY 7-(3-VINYL-1,4-PIPERAZINE-1-YL) | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-08 | — | — | WO | disclosed |
| EP-0610958-A3 | Intermediates in the preparation of 4-oxoquinoline-3-carboxylic acid derivatives. | UBE INDUSTRIES (JP) | 1995-03-22 | — | — | EP | disclosed |
| EP-0610958-A2 | Intermediates in the preparation of 4-oxoquinoline-3-carboxylic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1994-08-17 | — | — | EP | disclosed |
| EP-0306860-A3 | 4-OXO-3-QUINOLINECARBOXYLIC ACIDS USEFUL AS ANTIBACTERIAL AGENTS AND PREPARATION THEREOF | STERLING WINTHROP INC. (US) | 1990-07-18 | — | — | EP | disclosed |
| EP-0235676-B1 | 7-(1-PYRROLIDINYL)QUINOLONE-CARBOXYLIC-ACID DERIVATIVES | BAYER AG (DE) | 1990-06-13 | — | — | EP | disclosed |
| EP-0306860-A2 | 4-Oxo-3-Quinolinecarboxylic acids useful as antibacterial agents and preparation thereof | STERLING WINTHROP INC. (US) | 1989-03-15 | — | — | EP | disclosed |
| EP-0166939-A1 | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7(3-oxo-1-piperazinyl)-3-quinoline-carboxylic acids, process for their preparation and bactericidal agents containing them | BAYER AG (DE) | 1986-01-08 | — | — | EP | disclosed |
| EP-0117474-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |