⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL555027 | 0.82 | — | — | |
| SCHEMBL42855 | 0.80 | — | — | |
| SCHEMBL42856 | 0.80 | — | — | |
| SCHEMBL10940176 | 0.78 | — | — | |
| SCHEMBL10944752 | 0.78 | — | — | |
| SCHEMBL11054393 | 0.78 | — | — | |
| SCHEMBL28972436 | 0.75 | GSR (0.40) | — | |
| SCHEMBL8633356 | 0.73 | — | — | |
| SCHEMBL2264879 | 0.73 | — | — | |
| SCHEMBL10788422 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 380 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240182531-A1 | KV1.3 Blockers | ZEALAND PHARMA A/S (DK) | 2024-06-06 | — | — | US | claimed |
| WO-2024083919-A1 | INHIBITORS | ZEALAND PHARMA A/S (DK) | 2024-04-25 | — | — | WO | claimed |
| EP-4314024-A1 | KV1.3 BLOCKERS | Zealand Pharma A/S (DK) | 2024-02-07 | — | — | EP | claimed |
| CN-117255798-A | Kv1.3 blockers | 西兰制药公司 | 2023-12-19 | — | — | CN | claimed |
| US-20180215784-A1 | METHOD FOR PREPARATION OF N-ACYL PEPTIDES, POLYPEPTIDES AND PROTEINS | NEODEL TEC LTD. (IL) | 2018-08-02 | — | — | US | claimed |
| EP-3344646-A1 | METHOD FOR PREPARATION OF N-ACYL PEPTIDES, POLYPEPTIDES AND PROTEINS | Neodel Tec Ltd. (IL) | 2018-07-11 | — | — | EP | claimed |
| EP-1771206-B1 | LIPIDS, LIPID COMPLEXES AND USE THEREOF | SILENCE THERAPEUTICS GMBH (DE) | 2018-04-11 | — | — | EP | claimed |
| US-20170296469-A1 | LIPOPLEX FORMULATIONS FOR SPECIFIC DELIVERY TO VASCULAR ENDOTHELIUM | SILENCE THERAPEUTICS GMBH (DE) | 2017-10-19 | — | — | US | claimed |
| US-9486538-B2 | Lipids, lipid complexes and use thereof | SILENCE THERAPEUTICS GMBH (DE) | 2016-11-08 | — | — | US | claimed |
| WO-2016157177-A1 | METHOD FOR PREPARATION OF N-ACYL PEPTIDES, POLYPEPTIDES AND PROTEINS | NEODEL TEC LTD. (IL) | 2016-10-06 | — | — | WO | claimed |
| EP-0708770-B1 | AMIDE DERIVATIVES OF 16-MEMBERED RING ANTIBIOTIC MACROLIDES | PFIZER (US) | 1997-04-16 | — | — | EP | claimed |
| WO-1996040264-A1 | SEPARATION OF ACTIVE COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-12-19 | — | — | WO | claimed |
| EP-0642530-A1 | DERIVATIVES OF DOLASTATIN | BASF Aktiengesellschaft (DE) | 1995-03-15 | — | — | EP | claimed |
| EP-0370453-B1 | Peptides having a Brady kinine-inhibiting activity | HOECHST AG (DE) | 1994-06-15 | — | — | EP | claimed |
| WO-1993023424-A1 | DERIVATIVES OF DOLASTATIN | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-25 | — | — | WO | claimed |
| EP-0564972-A2 | Peptides with N-terminal modifications having bradykinin antagonistic activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-13 | — | — | EP | claimed |
| US-5171835-A | LHRH antagonists | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1992-12-15 | — | — | US | claimed |
| EP-0455133-A2 | Peptide antagonists of bradykinin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-06 | — | — | EP | claimed |
| EP-0413277-A1 | Peptide antagonists of bradykinin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-20 | — | — | EP | claimed |
| EP-0370453-A2 | Peptides having a Brady kinine-inhibiting activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | claimed |