Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.40 |
| ▸ | ESR1 | P03372 | 6/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816725 | 0.95 | ESR2 (0.43) | TP53CYP3A4TYRMEN1ALOX5 | |
| SCHEMBL3812675 | 0.85 | ESR2 (0.48) | CYP3A4ESR2ESR1 | |
| SCHEMBL2718788 | 0.84 | TP53 (0.51) | TP53CYP3A4TYRMEN1ALOX5 | |
| SCHEMBL2721546 | 0.84 | TP53 (0.51) | TP53CYP3A4TYRMEN1ALOX5 | |
| SCHEMBL2718706 | 0.84 | TP53 (0.51) | TP53CYP3A4TYRMEN1ALOX5 | |
| SCHEMBL9075191 | 0.83 | ESR1 (0.56) | TP53CYP3A4ESR2SPHK1ESR1 | |
| SCHEMBL9073983 | 0.83 | ESR1 (0.56) | TP53CYP3A4ESR2SPHK1ESR1 | |
| SCHEMBL9075573 | 0.83 | ESR1 (0.56) | TP53CYP3A4ESR2SPHK1ESR1 | |
| SCHEMBL2720022 | 0.82 | CYP3A4 (0.49) | TP53CYP3A4TYRMEN1ALOX5 | |
| SCHEMBL9279382 | 0.82 | ESR1 (0.54) | TP53CYP3A4ESR2SPHK1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375461-B1 | DIPHENOL AND PROCESS FOR PRODUCING THE SAME | HONSHU CHEMICAL IND (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6872858-B2 | Diphenol and process for producing the same | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-03-29 | — | — | US | disclosed |
| US-20040049086-A1 | Diphenol and process for producing the same | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1375461-A1 | DIPHENOL AND PROCESS FOR PRODUCING THE SAME | Honshu Chemical Industry Co. Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049086-A1 | Diphenol and process for producing the same | CYP1A1, AHR, CYP2E1 | TP53 3303/4885CYP3A4 44/4885TYR 377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.