Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.55 |
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.53 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821435 | 0.88 | TLR7 (0.57) | TLR8TLR7 | |
| SCHEMBL7249936 | 0.84 | TLR8 (0.67) | TLR8TLR7NUDT1 | |
| SCHEMBL3813408 | 0.83 | TLR7 (0.59) | TLR8TLR7 | |
| SCHEMBL728616 | 0.83 | TLR7 (0.69) | TLR8TLR7NUDT1 | |
| SCHEMBL3813290 | 0.82 | TLR7 (0.55) | TLR8TLR7 | |
| SCHEMBL726760 | 0.81 | TLR8 (0.63) | TLR8TLR7NUDT1 | |
| SCHEMBL3820436 | 0.80 | TLR7 (0.53) | TLR8TLR7 | |
| SCHEMBL728508 | 0.80 | TLR8 (0.58) | TLR8TLR7NUDT1 | |
| SCHEMBL3968461 | 0.78 | TLR7 (0.76) | TLR8TLR7NUDT1 | |
| SCHEMBL3832987 | 0.78 | TLR7 (0.55) | TLR8TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1642580-B1 | Sulfonamide substituted imidazoquinolines | COLEY PHARM GROUP INC (US) | 2009-08-19 | — | — | EP | claimed |