SCHEMBL3818445

SCHEMBL3818445

COC(=O)[C@H](C)NN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9523940 1.00
Hydrochloric Acid SCHEMBL28719593 0.97
Hydrochloric Acid SCHEMBL20304518 0.97
Hydrochloric Acid SCHEMBL20304471 0.97
SCHEMBL14621758 0.79 TSHR (0.42)
SCHEMBL15083848 0.79 TSHR (0.42)
SCHEMBL27732969 0.77
SCHEMBL14908423 0.77
SCHEMBL23019171 0.77
SCHEMBL29089183 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4562015-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 EP disclosed
WO-2024026481-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
EP-3756464-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2020-12-30 EP disclosed
EP-3151669-B1 USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2020-10-28 EP disclosed
US-10442777-B2 Use of substituted oxadiazoles for combating phytopathogenic fungi BASF SE (DE) 2019-10-15 US disclosed
US-20190016694-A1 USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2019-01-17 US disclosed
US-20170144980-A1 USE OF SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2017-05-25 US disclosed
EP-1436286-B1 FUMAGILLOL DERIVATIVES AND PREPARING METHOD THEREOF EQUISPHARM CO LTD (KR) 2009-08-19 EP disclosed
US-20070149613-A1 Fumagillol derivative and the medical use thereof EQUISPHARM CO., LTD. (KR) 2007-06-28 US disclosed
US-20060276512-A1 Fumagillol derivatives and preparing method thereof HAN CHEOL-KYU 2006-12-07 US disclosed
US-7087768-B2 6-O-(4-methoxyaniline)acetyl fumagillol for example; superior angiogenesis inhibitory effect with less toxicity, also a cancer metastasis inhibitor, and treats angiogenesis related disorders such as other various inflammatory diseases such as rheumatic disease, psoriasis, and diabetic retinopathy EQUISPHARM CO., LTD. (KR) 2006-08-08 US disclosed