Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764227 | 0.85 | MEN1 (0.52) | MEN1KMT2AKDM4EHTR2AALDH1A1 | |
| SCHEMBL8763171 | 0.83 | MEN1 (0.46) | MEN1KMT2AKDM4EHTR2AALDH1A1 | |
| SCHEMBL7029983 | 0.80 | MEN1 (0.41) | MEN1KMT2AKDM4EMAPTTAAR1 | |
| SCHEMBL8016874 | 0.80 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL31265560 | 0.80 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL1150682 | 0.79 | MEN1 (0.43) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL31324218 | 0.79 | MEN1 (0.43) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL9512782 | 0.77 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3LTA4HKDM4E | |
| SCHEMBL31324220 | 0.76 | TSHR (0.44) | MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL27939527 | 0.75 | CYP2A6 (0.36) | MEN1KMT2ACYP3A4TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620885-B1 | ORGANIC POLYMERS, ELECTRONIC DEVICES, AND METHODS | 3M INNOVATIVE PROPERTIES CO (US) | 2009-08-12 | — | — | EP | claimed |
| CN-103570683-B | Polysubstituted aminated compounds and its preparation method and application | 中国科学院上海药物研究所 | 2018-04-17 | — | — | CN | disclosed |
| CN-103570683-A | Multi-substituted amine compound, as well as preparation method and use thereof | SHANGHAI INST MATERIA MEDICA | 2014-02-12 | — | — | CN | disclosed |