Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28318422 | 0.88 | NR4A2 (0.69) | MAPTNR4A2ALDH1A1KDM4ENPC1 | |
| SCHEMBL23551087 | 0.87 | TUBB1 (0.67) | MAPTTUBB1NR4A2ALDH1A1KDM4E | |
| SCHEMBL590922 | 0.84 | MAPT (0.73) | MAPTTUBB1NR4A2ALDH1A1KDM4E | |
| SCHEMBL30075344 | 0.84 | MAPT (0.73) | MAPTTUBB1NR4A2ALDH1A1KDM4E | |
| SCHEMBL12480809 | 0.83 | MAPT (0.71) | MAPTTUBB1NR4A2ALDH1A1KDM4E | |
| SCHEMBL31501108 | 0.82 | NR4A2 (0.78) | MAPTTUBB1NR4A2ALDH1A1KDM4E | |
| SCHEMBL3660284 | 0.82 | MAPT (0.69) | MAPTTUBB1NR4A2ALDH1A1KDM4E | |
| SCHEMBL4236223 | 0.82 | NR4A2 (0.78) | MAPTTUBB1NR4A2ALDH1A1KDM4E | |
| SCHEMBL27273111 | 0.82 | MAPT (0.74) | MAPTTUBB1NR4A2ALDH1A1KDM4E | |
| SCHEMBL1559335 | 0.81 | MAPT (0.68) | MAPTTUBB1NR4A2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465880-B1 | 5-SULPHANYL-4H-1,2,4-TRIAZOLE DERIVATIVES AND THEIR USE TO TREAT DISORDERS ASSOCIATED WITH SOMATOSTATINE | IPSEN PHARMA (FR) | 2009-08-05 | — | — | EP | disclosed |
| EP-1465880-A1 | 5-SULPHANYL-4H-1,2,4-TRIAZOLE DERIVATIVES AND THEIR USE AS MEDICINE | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003045926-A1 | 5-SULPHANYL-4H-1,2,4-TRIAZOLE DERIVATIVES AND THEIR USE AS MEDICINE | SOCIETE DE CONSEILS DE RECHERCHE ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2003-06-05 | — | — | WO | disclosed |