⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275276 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL5860637 | 0.82 | — | — | |
| SCHEMBL525878 | 0.80 | — | — | |
| SCHEMBL2332294 | 0.77 | — | — | |
| Phosphoric Acid SCHEMBL1936777 | 0.76 | — | — | |
| SCHEMBL6747457 | 0.58 | — | — | |
| SCHEMBL436317 | 0.54 | — | — | |
| SCHEMBL8373708 | 0.49 | — | — | |
| SCHEMBL661517 | 0.49 | — | — | |
| SCHEMBL301634 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265083-A1 | SUBSTITUTED UREA DEPSIPEPTIDE ANALOGS AS ACTIVATORS OF THE CLPP ENDOPEPTIDASE | St. Jude Children's Research Hospital (US) | 2018-01-10 | — | — | EP | disclosed |
| EP-3223821-A1 | SUBSTITUTED PYRIDOBENZODIAZEPINONE-DERIVATIVES AND USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2017-10-04 | — | — | EP | disclosed |
| WO-2016083276-A1 | SUBSTITUTED PYRIDOBENZODIAZEPINONE-DERIVATIVES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-02 | — | — | WO | disclosed |
| US-8835472-B2 | Compounds, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-16 | — | — | US | disclosed |
| US-8765959-B2 | Piperidine derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-8759528-B2 | Piperidine derivatives, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-06-24 | — | — | US | disclosed |
| EP-2619178-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2013-07-31 | — | — | EP | disclosed |
| US-20130143876-A1 | New piperidine derivatives, pharmaceutical compositions and uses thereof | ROTH GERALD JUERGEN (DE) | 2013-06-06 | — | — | US | disclosed |
| US-8344004-B2 | Cyclic pyridyl-N-[1,3,4]-thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and their use as pharmaceuticals | SANOFI (FR) | 2013-01-01 | — | — | US | disclosed |
| US-8304556-B2 | Thiazolyl-dihydro-indazoles | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| WO-2001031057-A2 | DOUBLE-STRAND NUCLEIC ACID PROBES AND THE USE THEREOF | NANOGEN RECOGNOMICS GMBH (DE) | 2001-05-03 | — | — | WO | disclosed |
| WO-2001025264-A2 | SUBSTITUTED PHOSPHINATE BASED PEPTIDE DERIVATIVES | OSTEOPRO A/S (DK) | 2001-04-12 | — | — | WO | disclosed |
| EP-1061904-A1 | NANOPARTICLES, METHOD FOR PRODUCING NANOPARTICLES AND USE OF THE SAME | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-12-27 | — | — | EP | disclosed |
| WO-2000034394-A2 | PYRIDINE DYES AND QUINOLINE DYES USED AS MARKERS FOR BIOMOLECULES, POLYMERS, MEDICAMENTS, AND PARTICLES | WOLFBEIS OTTO SAMUEL (DE) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000032235-A1 | TRANSPORT SYSTEM CONJUGATE | PENTAPHARM AG (CH) | 2000-06-08 | — | — | WO | disclosed |
| WO-1999062882-A1 | SUBSTITUTED INDOLINONES, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-12-09 | — | — | WO | disclosed |
| WO-1999047130-A1 | NANOPARTICLES, METHOD FOR PRODUCING NANOPARTICLES AND USE OF THE SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-09-23 | — | — | WO | disclosed |
| EP-0942756-A2 | OPTICAL DIAGNOSTIC AGENTS FOR DIAGNOSIS OF NEURODEGENERATIVE DISEASES BY MEANS OF NEAR INFRA-RED RADIATION (NIR RADIATION) | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022146-A2 | OPTICAL DIAGNOSTIC AGENTS FOR DIAGNOSIS OF NEURODEGENERATIVE DISEASES BY MEANS OF NEAR INFRA-RED RADIATION (NIR RADIATION) | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 1998-05-28 | — | — | WO | disclosed |
| WO-1997006258-A2 | cDNA SEQUENCE, AMINO-ACID SEQUENCE, DERIVED FROM THE cDNA SEQUENCE, OF THE PRECURSOR PROTEIN OF HUMAN GCAP-II/UROGUANYLINE, AND AMINO-ACID SEQUENCE OF THE FRAGMENT CIRCULATING IN HUMAN BLOOD | FORSSMANN WOLF GEORG (DE) | 1997-02-20 | — | — | WO | disclosed |