Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 19/20 | 0.66 |
| ▸ | HCAR3 | P49019 | 15/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823110 | 0.87 | HCAR2 (0.60) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL3823775 | 0.85 | HCAR2 (0.65) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL3819466 | 0.84 | HCAR2 (0.66) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL3819252 | 0.82 | HCAR2 (0.66) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL3111157 | 0.80 | HCAR2 (1.00) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL11294532 | 0.77 | HCAR2 (0.60) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL3818988 | 0.77 | HCAR2 (0.65) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL3823505 | 0.76 | HCAR2 (0.66) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL3108382 | 0.76 | HCAR2 (0.74) | HCAR2HCAR3CYP1A2 | |
| SCHEMBL3819443 | 0.74 | HCAR2 (0.67) | HCAR2HCAR3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701947-B1 | 4-OXO-4,5-DIHYDRO-FURAN-2-CARBOXYLIC AND ACID DERIVATIVES AND METHODS OF TREATMENT OF METABOLIC-RELATED DISORDERS THEREOF | ARENA PHARM INC (US) | 2009-08-26 | — | — | EP | claimed |