Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 17/20 | 0.55 |
| ▸ | RARB | P10826 | 16/20 | 0.55 |
| ▸ | RARA | P10276 | 15/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382486 | 0.89 | RARG (0.59) | RARGRARBRARAPTPN11 | |
| SCHEMBL382116 | 0.88 | RARG (0.57) | RARGRARBRARAPTPN11 | |
| SCHEMBL382470 | 0.83 | RARG (0.68) | RARGRARBRARAPTPN11 | |
| SCHEMBL29367636 | 0.82 | RARG (0.71) | RARGRARBRARA | |
| SCHEMBL382998 | 0.81 | RARG (0.70) | RARGRARBRARAPTPN11 | |
| SCHEMBL383178 | 0.77 | RARG (0.75) | RARGRARBRARAPTPN11 | |
| SCHEMBL383193 | 0.75 | RARG (0.65) | RARGRARBRARAPTPN11 | |
| SCHEMBL382759 | 0.75 | RARB (0.57) | RARGRARBRARA | |
| SCHEMBL382938 | 0.72 | RARG (0.66) | RARGRARBRARAPTPN11 | |
| SCHEMBL29488619 | 0.72 | RARB (0.52) | RARBRARAPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831149-B1 | NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2012-01-25 | — | — | EP | disclosed |