SCHEMBL382144

SCHEMBL382144

NC(C(=O)O)C(N)S(=O)(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 14/20 0.54
SLC1A3 P43003 13/20 0.54
SLC1A1 P43005 11/20 0.54
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
PLA2G7 Q13093 1/20 0.41
CA9 Q16790 1/20 0.41
CA13 Q8N1Q1 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7651611 1.00 SLC1A2 (0.54) SLC1A2SLC1A3SLC1A1CA12CA1
Hydrochloric Acid SCHEMBL382914 0.98 SLC1A2 (0.53) SLC1A2SLC1A3SLC1A1CA12CA1
SCHEMBL8861438 0.83 SLC1A2 (0.41) SLC1A2SLC1A3SLC1A1CA12CA1
SCHEMBL9094528 0.83 SLC1A3 (0.58) SLC1A2SLC1A3SLC1A1CA12CA1
SCHEMBL7372101 0.83 SLC1A3 (0.58) SLC1A2SLC1A3SLC1A1CA12CA1
SCHEMBL8861442 0.83 SLC1A2 (0.41) SLC1A2SLC1A3SLC1A1CA12CA1
SCHEMBL6009004 0.81 SLC1A3 (0.46) SLC1A2SLC1A3SLC1A1ALDH1A1MAPT
SCHEMBL6009009 0.81 SLC1A3 (0.46) SLC1A2SLC1A3SLC1A1ALDH1A1MAPT
SCHEMBL7452284 0.80 CA12 (0.45) SLC1A2SLC1A3SLC1A1CA12CA1
Hydrochloric Acid SCHEMBL7373021 0.80 SLC1A3 (0.44) SLC1A2SLC1A3SLC1A1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0730590-A1 NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-09-11 EP claimed
WO-1995014683-A1 NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-06-01 WO claimed
EP-1074543-B1 AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS MEIJI SEIKA PHARMA CO LTD (JP) 2012-01-25 EP disclosed
EP-1049693-A1 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS $g(a) v?$g(b) 3? ANTAGONISTS Du Pont Pharmaceuticals Company (US) 2000-11-08 EP disclosed
WO-1999026945-A1 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS αvβ3 ANTAGONISTS DU PONT PHARMACEUTICALS COMPANY (US) 1999-06-03 WO disclosed