Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821557 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2TDP1CHRM1AKR1A1 | |
| SCHEMBL3821560 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2TDP1CHRM1AKR1A1 | |
| SCHEMBL3222107 | 0.95 | GRIK1 (0.50) | GRIK1GRIK2TDP1CHRM1AKR1A1 | |
| SCHEMBL3222115 | 0.95 | GRIK1 (0.50) | GRIK1GRIK2TDP1CHRM1AKR1A1 | |
| SCHEMBL2229237 | 0.85 | GRIK1 (0.58) | GRIK1GRIK2TDP1ALDH1A1CYP19A1 | |
| SCHEMBL3824909 | 0.85 | GRIK1 (0.58) | GRIK1GRIK2TDP1ALDH1A1CYP19A1 | |
| SCHEMBL12099047 | 0.85 | GRIK1 (0.58) | GRIK1GRIK2TDP1ALDH1A1CYP19A1 | |
| SCHEMBL2754220 | 0.85 | GRIK1 (0.58) | GRIK1GRIK2TDP1ALDH1A1CYP19A1 | |
| SCHEMBL2754222 | 0.85 | GRIK1 (0.58) | GRIK1GRIK2TDP1ALDH1A1CYP19A1 | |
| SCHEMBL2754221 | 0.85 | GRIK1 (0.58) | GRIK1GRIK2TDP1ALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094640-A1 | ALPHA-SUBSTITUTED OMEGA-3 LIPIDS THAT ARE ACTIVATORS OR MODULATORS OF THE PEROXISOME PROLIFERATORS-ACTIVATED RECEPTOR (PPAR). | Pronova BioPharma Norge AS (NO) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008053331-A1 | ALPHA-SUBSTITUTED OMEGA-3 LIPIDS THAT ARE ACTIVATORS OR MODULATORS OF THE PEROXISOME PROLIFERATORS-ACTIVATED RECEPTOR (PPAR). | PRONOVA BIOPHARMA NORGE A/S (SE) | 2008-05-08 | — | — | WO | disclosed |