SCHEMBL382183

SCHEMBL382183

CCN(CC)c1ccc(-c2cc(-c3ccc(OC(=O)O)cc3)ccc2OCCCCO)cc1C(C)(C)C

nearest known ligand 0.80

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RARG P13631 20/20 0.80
RARB P10826 19/20 0.80
RARA P10276 18/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL383242 0.97 RARG (0.79) RARGRARBRARA
SCHEMBL381528 0.95 RARG (0.79) RARGRARBRARA
SCHEMBL382661 0.92 RARG (0.69) RARGRARBRARA
SCHEMBL382966 0.90 RARG (0.70) RARGRARBRARA
SCHEMBL382238 0.89 RARG (0.65) RARGRARBRARA
SCHEMBL382382 0.89 RARG (1.00) RARGRARBRARA
SCHEMBL383424 0.88 RARG (0.67) RARGRARBRARA
SCHEMBL382560 0.88 RARG (0.62) RARGRARBRARA
SCHEMBL382524 0.87 RARG (0.66) RARGRARBRARA
SCHEMBL381691 0.86 RARG (1.00) RARGRARBRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1831149-B1 NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS GALDERMA RES & DEV (FR) 2012-01-25 EP claimed