Phosphine

Phosphine

SCHEMBL3822065

CCCCO[N+](=O)OCCCC.P

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.46
TSHR P16473 4/20 0.39
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
ALDH1A1 P00352 3/20 0.39
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
ATM Q13315 1/20 0.36
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL326036 0.97 CYP3A4 (0.42) CYP3A4TSHRADRB2ADRB1ADRB3
Water SCHEMBL11127184 0.94 CYP3A4 (0.40) CYP3A4TSHRADRB2ADRB1ADRB3
Ammonia Solution, Strong SCHEMBL5550497 0.94 CYP3A4 (0.40) CYP3A4TSHRADRB2ADRB1ADRB3
SCHEMBL324579 0.89 CA1 (0.41) TSHRALDH1A1CA1CA2HPGD
SCHEMBL3639078 0.87 TSHR (0.46) CYP3A4TSHRADRB2ADRB1ADRB3
SCHEMBL273331 0.86 CA1 (0.43) TSHRALDH1A1CA1CA2HPGD
SCHEMBL324701 0.86 CA1 (0.43) TSHRALDH1A1CA1CA2HPGD
SCHEMBL326032 0.86 CA1 (0.43) TSHRALDH1A1CA1CA2HPGD
SCHEMBL11232265 0.86 CA1 (0.43) TSHRALDH1A1CA1CA2HPGD
SCHEMBL9542977 0.86 CA1 (0.43) TSHRALDH1A1CA1CA2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090226616-A1 FOUNTAIN SOLUTION COMPOSITION FOR LITHOGRAPHIC PRINTING AND HEAT-SET OFFSET ROTARY PRINTING PROCESS FUJIFILM CORPORATION (JP) 2009-09-10 US disclosed
EP-2098377-A2 Fountain solution composition for lithographic printing and heat-set offset rotary printing process FUJIFILM Corporation (JP) 2009-09-09 EP disclosed