Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 13/20 | 0.66 |
| ▸ | RARA | P10276 | 12/20 | 0.66 |
| ▸ | RARB | P10826 | 12/20 | 0.66 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382688 | 0.91 | RARG (0.64) | RARGRARARARBSLC6A9PPARG | |
| SCHEMBL383438 | 0.90 | RARG (0.78) | RARGRARARARBSLC6A9 | |
| SCHEMBL382029 | 0.89 | RARG (0.83) | RARGRARARARB | |
| SCHEMBL382310 | 0.89 | RARG (0.80) | RARGRARARARBSLC6A9 | |
| SCHEMBL25747751 | 0.89 | RARG (0.68) | RARGRARARARBSLC6A9MEN1 | |
| SCHEMBL382355 | 0.89 | RARG (0.80) | RARGRARARARBSLC6A9 | |
| SCHEMBL25747756 | 0.88 | RARG (0.72) | RARGRARARARBSLC6A9 | |
| SCHEMBL25040287 | 0.87 | RARG (0.70) | RARGRARARARBSLC6A9GAA | |
| SCHEMBL25038342 | 0.86 | RARG (0.64) | RARGRARARARBGAAMAPT | |
| SCHEMBL30244992 | 0.86 | RARG (0.64) | RARGRARARARBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831149-B1 | NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2012-01-25 | — | — | EP | claimed |