SCHEMBL3822280

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3820664	0.83	ATM (0.47)	ATMHCAR2CYP2C19CYP2C9KDM4E
	SCHEMBL5093092	0.79	ATM (0.44)	ATMHCAR2CYP2C19CYP2C9KDM4E
	SCHEMBL11166563	0.78	KDM4E (0.51)	KDM4EALDH1A1HPGDL3MBTL1HTT
	SCHEMBL27643217	0.77	HCAR2 (0.51)	ATMHCAR2CYP2C19CYP2C9KDM4E
	SCHEMBL2198776	0.77	KMT2A (0.44)	KDM4EALDH1A1HPGDHSD17B10L3MBTL1
	SCHEMBL3821933	0.77	KDM4E (0.46)	ATMHCAR2CYP2C19CYP2C9KDM4E
	SCHEMBL6979199	0.76	CYP2C19 (0.72)	ATMHCAR2CYP2C19CYP2C9ALDH1A1
	SCHEMBL3823338	0.75	CYP2C19 (0.46)	ATMHCAR2CYP2C19CYP2C9KDM4E
	SCHEMBL3828192	0.74	CYP2C19 (0.45)	ATMHCAR2CYP2C19CYP2C9KDM4E
	SCHEMBL2036336	0.73	NPC1 (0.54)	ALDH1A1CYP3A4SMN1; SMN2RAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.