Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.53 |
| ▸ | CNR1 | P21554 | 9/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3818973 | 0.85 | CNR1 (0.70) | CNR2CNR1PPARA | |
| SCHEMBL3822505 | 0.83 | CNR1 (0.64) | CNR2CNR1PPARA | |
| SCHEMBL4885237 | 0.83 | CNR1 (0.52) | CNR2CNR1PPARA | |
| SCHEMBL3833353 | 0.83 | CNR2 (0.61) | CNR2CNR1PPARA | |
| SCHEMBL3814725 | 0.80 | CNR1 (0.54) | CNR2CNR1PPARA | |
| SCHEMBL4599848 | 0.76 | CNR1 (0.64) | CNR2CNR1PPARA | |
| SCHEMBL4612333 | 0.75 | CNR1 (0.57) | CNR2CNR1PPARA | |
| SCHEMBL4611288 | 0.75 | CNR2 (0.57) | CNR2CNR1PPARA | |
| SCHEMBL29838939 | 0.75 | CNR2 (0.68) | CNR2CNR1PPARA | |
| SCHEMBL4599761 | 0.74 | CNR1 (0.73) | CNR2CNR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718617-B1 | 3-SUBSTITUTED 1,5-DIPHENYLPYRAZOLE DERIVATIVES USEFUL AS CB1 MODULATORS | ASTRAZENECA AB (SE) | 2009-08-19 | — | — | EP | claimed |