Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 12/20 | 1.00 |
| ▸ | CYP11B2 | P19099 | 12/20 | 1.00 |
| ▸ | IDO1 | P14902 | 7/20 | 0.79 |
| ▸ | HPGDS | O60760 | 1/20 | 0.62 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1501929 | 0.89 | CYP11B1 (1.00) | CYP11B1CYP11B2IDO1HPGDSP2RX7 | |
| SCHEMBL1949527 | 0.86 | CYP11B1 (1.00) | CYP11B1CYP11B2IDO1HPGDSP2RX7 | |
| SCHEMBL3823466 | 0.86 | CYP11B1 (1.00) | CYP11B1CYP11B2IDO1HPGDSP2RX7 | |
| SCHEMBL1948768 | 0.84 | CYP11B1 (0.79) | CYP11B1CYP11B2IDO1HPGDSP2RX7 | |
| SCHEMBL1951962 | 0.84 | CYP11B1 (0.79) | CYP11B1CYP11B2IDO1HPGDSP2RX7 | |
| SCHEMBL3968209 | 0.84 | CYP11B1 (0.79) | CYP11B1CYP11B2IDO1HPGDSP2RX7 | |
| SCHEMBL3968212 | 0.84 | CYP11B1 (0.79) | CYP11B1CYP11B2IDO1HPGDSP2RX7 | |
| SCHEMBL3969042 | 0.82 | CYP11B1 (0.74) | CYP11B1CYP11B2IDO1HPGDSP2RX7 | |
| SCHEMBL3972715 | 0.81 | CYP11B1 (0.79) | CYP11B1CYP11B2IDO1HPGDSP2RX7 | |
| SCHEMBL12544753 | 0.81 | CYP11B1 (0.72) | CYP11B1CYP11B2IDO1HPGDSP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106640-A2 | N-BENZYL IMIDAZOLE DERIVATIVES | MAASTRICHT UNIVERSITY (NL) | 2009-09-03 | — | — | WO | disclosed |
| EP-2095819-A1 | N-benzyl imidazole derivatives and their use as aldosterone synthase inhibitors | Maastricht University (NL) | 2009-09-02 | — | — | EP | disclosed |
| EP-2095819-A1 | N-benzyl imidazole derivatives and their use as aldosterone synthase inhibitors | Maastricht University (NL) | 2009-09-02 | — | — | EP | disclosed |