Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460817 | 0.88 | TYRO3 (0.57) | TYRO3ATR | |
| SCHEMBL3461204 | 0.88 | TYRO3 (0.57) | TYRO3ATR | |
| SCHEMBL3462250 | 0.86 | ATR (0.56) | TYRO3ATR | |
| SCHEMBL3460391 | 0.86 | ATR (0.56) | TYRO3ATR | |
| SCHEMBL3460197 | 0.85 | ATR (0.56) | TYRO3ATR | |
| SCHEMBL3823950 | 0.85 | TYRO3 (0.55) | TYRO3ATR | |
| SCHEMBL3820905 | 0.85 | ATR (0.56) | TYRO3ATR | |
| SCHEMBL3462142 | 0.83 | PIK3CD (0.58) | ATR | |
| SCHEMBL3461001 | 0.83 | TYRO3 (0.54) | TYRO3ATR | |
| SCHEMBL3462042 | 0.82 | TYRO3 (0.61) | TYRO3ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501514-A4 | PROTEIN KINASE MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2009-08-26 | — | — | EP | disclosed |
| EP-1501514-A2 | PROTEIN KINASE MODULATORS AND METHODS OF USE | Exelixis, Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093297-A2 | PROTEIN KINASE MODULATORS AND METHODS OF USE | EXELIXIS, INC. (US) | 2003-11-13 | — | — | WO | disclosed |