SCHEMBL3824253

SCHEMBL3824253

CC[Zr](Cl)(Cl)(C1C(C)=Cc2c(-c3ccccc3)cccc21)C1C(C)=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
HTR7 P34969 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5223075 0.87 BCHE (0.32) PDCD1CD274
SCHEMBL7906413 0.85 PDCD1 (0.33) PDCD1CD274
SCHEMBL7630525 0.84 PDCD1 (0.34) PDCD1CD274
SCHEMBL27544313 0.83 PDCD1 (0.33) PDCD1CD274
SCHEMBL8853355 0.83 PDCD1 (0.32) PDCD1CD274HTR7
SCHEMBL139123 0.83 PDCD1 (0.32) PDCD1CD274
SCHEMBL6012049 0.83 PDCD1 (0.31) PDCD1CD274
SCHEMBL4660557 0.83 PDCD1 (0.31) PDCD1CD274
Hydrochloric Acid SCHEMBL15329571 0.82 PDCD1 (0.33) PDCD1CD274
SCHEMBL1240922 0.82 PDCD1 (0.31) PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2020420-B1 High crystalline polypropylene waxes CLARIANT FINANCE BVI LTD (VG) 2012-10-10 EP claimed
US-20090036619-A1 Highly crystalline polypropylene waxes CLARIANT INTERNATIONAL LTD. 2009-02-05 US disclosed
WO-2003037937-A1 DIENE FUNCTIONALIZED CATALYST SUPPORTS AND SUPPORTED CATALYST COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 2003-05-08 WO disclosed
US-20010021755-A1 Metallocenes containing aryl-substituted indenyl derivatives as ligands, process for their preparation, and their use as catalysts KUBER FRANK (DE) 2001-09-13 US disclosed
US-6255506-B1 SUPPORTED SYSTEM IN POLYMERIZATION OR COPOLYMERIZATION OF HIGH MOLECULAR WEIGHT POLYOLEFINS OF HIGH ISOTACTICITY AND NARROW MOLECULAR-WEIGHT DISTRIBUTION; FILMS, SHEETS OR LARGE HOLLOW ARTICLES OR MOLDINGS TARGOR GMBH (DE) 2001-07-03 US disclosed
US-6242544-B1 POLYOLEFINS PREPARED USING SOLUBLE METALLOCENE COMPOUNDS IN COMBINATION WITH ALUMINOXANES; HIGH MOLECULAR WEIGHT AND ISOTACTICITY TARGOR GMBH (DE) 2001-06-05 US disclosed
US-5840644-A OLEFIN POLYMERIZATION CATALYSTS TARGOR GMBH (DE) 1998-11-24 US disclosed
US-5786432-A POLYMERIZING OR COPOLYMERIZING OLEFIN IN PRESENCE OF TRANSITION METAL METALLOCENE CATALYST AND COCATALYST TARGOR GMBH (DE) 1998-07-28 US disclosed
US-5770753-A ADDITION POLYMERIZATION CATALYST TARGOR GMBH (DE) 1998-06-23 US disclosed