Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 16/20 | 0.56 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826954 | 0.94 | CETP (0.64) | CETP | |
| SCHEMBL1382256 | 0.89 | CETP (0.59) | CETPTACR1 | |
| SCHEMBL3824515 | 0.85 | CETP (0.63) | CETP | |
| SCHEMBL3830222 | 0.84 | CETP (0.53) | CETPTACR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3829802 | 0.83 | CETP (0.55) | CETP | |
| SCHEMBL3534091 | 0.82 | CETP (0.68) | CETP | |
| SCHEMBL1384297 | 0.81 | CETP (0.50) | CETP | |
| SCHEMBL6585798 | 0.80 | CETP (0.71) | CETP | |
| SCHEMBL6585801 | 0.80 | CETP (0.71) | CETP | |
| SCHEMBL1383056 | 0.80 | CETP (0.58) | CETPTACR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670768-B1 | COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA | LILLY CO ELI (US) | 2009-09-09 | — | — | EP | claimed |