Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | NCF1 | P14598 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | NQO1 | P15559 | 1/20 | 0.54 |
| ▸ | F2R | P25116 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29597329 | 0.87 | HDAC8 (0.66) | HDAC8HDAC6HDAC2HDAC1NCF1 | |
| SCHEMBL1337274 | 0.83 | HDAC8 (0.61) | HDAC8HDAC6HDAC2HDAC1NCF1 | |
| SCHEMBL27765943 | 0.82 | MAPT (0.59) | HDAC8HDAC6HDAC2HDAC1NCF1 | |
| SCHEMBL14912423 | 0.81 | HDAC8 (0.59) | HDAC8HDAC6HDAC2HDAC1NCF1 | |
| SCHEMBL14912427 | 0.81 | HDAC8 (0.59) | HDAC8HDAC6HDAC2HDAC1NCF1 | |
| SCHEMBL29022054 | 0.80 | HDAC8 (0.62) | HDAC8HDAC6HDAC2HDAC1NCF1 | |
| SCHEMBL30442203 | 0.80 | HDAC8 (0.62) | HDAC8HDAC6HDAC2HDAC1NCF1 | |
| SCHEMBL31018924 | 0.79 | HDAC8 (0.60) | HDAC8HDAC6HDAC2HDAC1NCF1 | |
| SCHEMBL19076213 | 0.78 | KDM4E (0.61) | HDAC8HDAC6HDAC2HDAC1NCF1 | |
| SCHEMBL29021885 | 0.78 | KDM4E (0.61) | HDAC8HDAC6HDAC2HDAC1NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101591291-A | The synthetic method of 2-ethenyl quinoline compound | INST MATERIA MEDICA CAMS (CN) | 2009-12-02 | — | — | CN | claimed |
| CN-101591291-B | Synthesis method of 2-ethenyl quinoline compound | INST MATERIA MEDICA CAMS | 2012-07-18 | — | — | CN | disclosed |
| CN-101591291-A | The synthetic method of 2-ethenyl quinoline compound | INST MATERIA MEDICA CAMS (CN) | 2009-12-02 | — | — | CN | disclosed |
| EP-1796466-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | disclosed |
| EP-1796466-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006002047-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-01-05 | — | — | WO | disclosed |
| EP-0538789-B1 | Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from vinyl compounds containing heterocyclic nitrogen groups | BRIDGESTONE CORP (JP) | 1995-12-13 | — | — | EP | disclosed |
| EP-0538789-A1 | Diene polymers having reduced hysteresis and improved raw viscosity incorporating primary partial coupling and terminals formed from vinyl compounds containing heterocyclic nitrogen groups | BRIDGESTONE CORPORATION (JP) | 1993-04-28 | — | — | EP | disclosed |