SCHEMBL38256

SCHEMBL38256

O=c1nc(NC2O[C@H](CO)[C@@H](O)[C@@H]2O)cc[nH]1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
CA1 P00915 9/20 0.45
CA2 P00918 9/20 0.45
GSK3B P49841 1/20 0.44
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
CA12 O43570 3/20 0.41
CA9 Q16790 3/20 0.41
GRK6 P43250 2/20 0.41
ADK P55263 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8711595 1.00 TSHR (0.46) TSHRCA1CA2GSK3BNPC1
SCHEMBL788634 1.00 TSHR (0.46) TSHRCA1CA2GSK3BNPC1
SCHEMBL375915 1.00 TSHR (0.46) TSHRCA1CA2GSK3BNPC1
SCHEMBL7030562 1.00 TSHR (0.46) TSHRCA1CA2GSK3BNPC1
SCHEMBL11289015 1.00 TSHR (0.46) TSHRCA1CA2GSK3BNPC1
SCHEMBL7198908 1.00 TSHR (0.46) TSHRCA1CA2GSK3BNPC1
SCHEMBL4278638 1.00 TSHR (0.46) TSHRCA1CA2GSK3BNPC1
SCHEMBL319584 1.00 TSHR (0.46) TSHRCA1CA2GSK3BNPC1
SCHEMBL4704343 1.00 TSHR (0.46) TSHRCA1CA2GSK3BNPC1
SCHEMBL7528649 0.99 TSHR (0.48) TSHRCA1CA2GSK3BNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4621 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111589-A1 COMPOSITIONS AND METHODS FOR ENHANCING DRUG RESISTANCE IN CELLS MEDICI THERAPEUTICS, INC. (US) 2025-05-30 WO claimed
WO-2024040220-A9 CD83 BINDING FUSION PROTEINS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2025-02-27 WO claimed
US-20250009778-A1 KRAS ANTAGONISTS TRUETIVA INC (US) 2025-01-09 US claimed
US-20240358708-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING LYMPHOID MALIGNANCY Diacovo, Thomas (US) 2024-10-31 US claimed
US-12116400-B2 Albumin variants and conjugates SARTORIUS ALBUMEDIX LIMITED (GB) 2024-10-15 US claimed
US-20240199738-A1 MONOCLONAL ANTIBODIES AND CONJUGATES AGAINST PROSTAGLANDIN F2 RECEPTOR INHIBITOR AND USES THEREOF A & G PHARMACEUTICAL INC (US) 2024-06-20 US claimed
WO-2024118760-A1 PEPTIDE-LINKED DRUG DELIVERY SYSTEM CORNELL UNIVERSITY (US) 2024-06-06 WO claimed
US-11969428-B2 Methods and pharmaceutical compositions for treating lymphoid malignancy Diacovo, Thomas (US) 2024-04-30 US claimed
EP-3243835-B1 ALBUMIN VARIANTS AND CONJUGATES ALBUMEDIX LTD (GB) 2024-04-10 EP claimed
US-11952353-B2 STAT3 transcription factor inhibitors and methods of using the same THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2024-04-09 US claimed
EP-0531452-A1 SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES NeXstar Pharmaceuticals, Inc. (US) 1993-03-17 EP claimed
WO-1991018914-A1 SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES VICAL, INC. (US) 1991-12-12 WO claimed
EP-0190050-B1 METHOD FOR PREPARING SMALL VESICLES USING MICROEMULSIFICATION VESTAR, INC. (US) 1991-05-15 EP claimed
EP-0409227-A2 Pyrimidine nucleosides, their preparation and pharmaceutical preparations MATTHES, Eckart, Dr. (DE) 1991-01-23 EP claimed
US-4753788-A HOMOGENIZING LIPIDS VESTAR RESEARCH INC. (US) 1988-06-28 US claimed
EP-0190050-A2 Method for preparing small vesicles using microemulsification VESTAR, INC. (US) 1986-08-06 EP claimed
US-4385112-A CULTURES, PSEUDOMONAS, QUANTITATIVE NUCLEOSIDE ASSAY, MAKING NUCLEOSIDE-5-CARBOXYLIC ACIDS TOYO JOZO KABUSHIKI KAISHA (JP) 1983-05-24 US claimed
EP-0034424-A2 Seven-membered ring compounds as inhibitors of cytidine deaminase THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1981-08-26 EP claimed
WO-1981002164-A1 SEVEN-MEMBERED RING COMPOUNDS AS INHIBITORS OF CYTIDINE DEAMINASE US COMMERCE (US) 1981-08-06 WO claimed
US-4275057-A CANCER AND ANTITUMOR DRUG RESEARCH THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1981-06-23 US claimed