⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51118 | 0.71 | — | — | |
| SCHEMBL1493104 | 0.69 | — | — | |
| SCHEMBL9262395 | 0.67 | — | — | |
| SCHEMBL1406158 | 0.67 | — | — | |
| SCHEMBL22265038 | 0.67 | — | — | |
| SCHEMBL4622061 | 0.67 | — | — | |
| SCHEMBL3752206 | 0.67 | — | — | |
| SCHEMBL18943024 | 0.65 | — | — | |
| SCHEMBL9357249 | 0.65 | — | — | |
| SCHEMBL30058644 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635685-B2 | Bifunctional antibiotics for targeting rRNA and resistance-causing enzymes and for inhibition of anthrax lethal factor | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2009-12-22 | — | — | US | claimed |
| US-20050148522-A1 | Bifunctional antibiotics for targeting rRNA and resistance-causing enzymes and for inhibition of anthrax lethal factor | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. | 2005-07-07 | — | — | US | claimed |
| US-20050004052-A1 | Bifunctional antibiotics for targeting rRNA and resistance-causing enzymes | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. | 2005-01-06 | — | — | US | claimed |
| US-8968997-B2 | Benzoxazole-based fluorescent metal ion indicators | Life Technologies Corporation (US) | 2015-03-03 | — | — | US | disclosed |
| US-20140045171-A1 | BENZOXAZOLE-BASED FLUORESCENT METAL ION INDICATORS | Life Technologies Corporation (US) | 2014-02-13 | — | — | US | disclosed |
| US-8540521-B2 | Benzoxazole-based fluorescent metal ion indicators | Life Technologies Corporation (US) | 2013-09-24 | — | — | US | disclosed |
| US-20110306082-A1 | \"BENZOXAZOLE-BASED FLUORESCENT METAL ION INDICATORS\ | Life Technologies Corporation (US) | 2011-12-15 | — | — | US | disclosed |
| US-7635685-B2 | Bifunctional antibiotics for targeting rRNA and resistance-causing enzymes and for inhibition of anthrax lethal factor | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2009-12-22 | — | — | US | disclosed |
| EP-1789429-B1 | BIFUNCTIONAL ANTIBIOTICS FOR TARGETING RRNA AND RESISTANCE CAUSING ENZYMES AND FOR INHIBITION OF ANTHRAX LETHAL FACTOR | TECHNION RES & DEV FOUNDATION (IL) | 2009-08-26 | — | — | EP | disclosed |
| US-20050148522-A1 | Bifunctional antibiotics for targeting rRNA and resistance-causing enzymes and for inhibition of anthrax lethal factor | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. | 2005-07-07 | — | — | US | disclosed |
| US-20050004052-A1 | Bifunctional antibiotics for targeting rRNA and resistance-causing enzymes | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. | 2005-01-06 | — | — | US | disclosed |
| CN-1090709-A | Bromine third phosphorus-parathion-methyl emulsion | INST OF PLANT PROTECTION CHINE (CN) | 1994-08-17 | — | — | CN | disclosed |