Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 12/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576461 | 0.89 | CNR2 (0.43) | EGLN1L3MBTL1EP300KAT2AKAT2B | |
| SCHEMBL2576312 | 0.89 | EGLN1 (0.51) | EGLN1L3MBTL1HIF1A | |
| SCHEMBL2582204 | 0.86 | EGLN1 (0.60) | EGLN1HIF1A | |
| SCHEMBL2581097 | 0.85 | HIF1A (0.57) | EGLN1HIF1A | |
| SCHEMBL2585485 | 0.84 | EGLN1 (0.51) | EGLN1HIF1A | |
| SCHEMBL2583340 | 0.83 | EGLN1 (0.56) | EGLN1HIF1A | |
| SCHEMBL2578875 | 0.83 | EGLN1 (0.52) | EGLN1HIF1A | |
| SCHEMBL2582349 | 0.82 | EGLN1 (0.60) | EGLN1HIF1A | |
| SCHEMBL2574737 | 0.82 | EGLN1 (0.52) | EGLN1HIF1A | |
| SCHEMBL2578353 | 0.81 | HIF1A (0.51) | EGLN1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097416-A1 | AZAQUINOLONE BASED COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF | Amgen, Inc (US) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008076425-A1 | AZAQUINOLONE BASED COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF | AMGEN INC. (US) | 2008-06-26 | — | — | WO | disclosed |