Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826291 | 0.91 | POLB (0.58) | POLBP2RX7ALDH1A1KMT2ATSHR | |
| SCHEMBL15042019 | 0.86 | POLB (0.66) | POLBP2RX7ALDH1A1KMT2ATSHR | |
| SCHEMBL12145251 | 0.85 | POLB (0.68) | POLBP2RX7ALDH1A1KMT2ATSHR | |
| SCHEMBL3824098 | 0.83 | POLB (0.66) | POLBP2RX7ALDH1A1KMT2ATSHR | |
| SCHEMBL1360703 | 0.81 | POLB (0.62) | POLBP2RX7ALDH1A1KMT2ATSHR | |
| SCHEMBL15042171 | 0.80 | POLB (0.69) | POLBP2RX7ALDH1A1KMT2AMEN1 | |
| SCHEMBL3843203 | 0.79 | POLB (0.59) | POLBP2RX7ALDH1A1KMT2ATSHR | |
| SCHEMBL12667786 | 0.79 | POLB (0.59) | POLBP2RX7ALDH1A1KMT2ATSHR | |
| SCHEMBL15042178 | 0.77 | POLB (0.57) | POLBP2RX7ALDH1A1KMT2AMEN1 | |
| SCHEMBL15042018 | 0.77 | POLB (0.52) | POLBALDH1A1KMT2ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722589-B2 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-05-13 | — | — | US | disclosed |
| US-20090042747-A1 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT INTERNATIONAL LTD. | 2009-02-12 | — | — | US | disclosed |