Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12667786 | 0.93 | POLB (0.59) | POLBKMT2ACYP2C19MEN1L3MBTL1 | |
| SCHEMBL1360703 | 0.93 | POLB (0.62) | POLBKMT2ACYP2C19MEN1L3MBTL1 | |
| SCHEMBL12145251 | 0.89 | POLB (0.68) | POLBKMT2ACYP2C19MEN1L3MBTL1 | |
| SCHEMBL15042178 | 0.88 | POLB (0.57) | POLBKMT2ACYP2C19MEN1L3MBTL1 | |
| SCHEMBL15042180 | 0.84 | POLB (0.48) | POLBKMT2ACYP2C19MEN1L3MBTL1 | |
| SCHEMBL15042019 | 0.82 | POLB (0.66) | POLBKMT2ACYP2C19MEN1L3MBTL1 | |
| SCHEMBL12667789 | 0.81 | KMT2A (0.62) | POLBKMT2ACYP2C19MEN1L3MBTL1 | |
| SCHEMBL3823291 | 0.81 | BRD4 (0.54) | KMT2ACYP2C19MEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL3826281 | 0.80 | POLB (0.53) | POLBKMT2ACYP2C19MEN1L3MBTL1 | |
| SCHEMBL15042126 | 0.80 | POLB (0.46) | POLBKMT2ACYP2C19MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722589-B2 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-05-13 | — | — | US | disclosed |
| US-20090042747-A1 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT INTERNATIONAL LTD. | 2009-02-12 | — | — | US | disclosed |