Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 8/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | TEK | Q02763 | 3/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3828244 | 0.89 | CYP1A2 (0.55) | CYP1A2CYP3A4TSHRALDH1A1HSD17B10 | |
| SCHEMBL3829044 | 0.88 | CYP1A2 (0.65) | CYP1A2CYP3A4TSHRALDH1A1HSD17B10 | |
| SCHEMBL13897858 | 0.84 | KDR (0.51) | CYP1A2CYP3A4TSHRALDH1A1HSD17B10 | |
| SCHEMBL3830759 | 0.84 | KDR (0.65) | MAPK14KDRTEKBRAFLCK | |
| SCHEMBL13898185 | 0.83 | BRAF (0.56) | CYP1A2CYP3A4TSHRALDH1A1HSD17B10 | |
| SCHEMBL3821613 | 0.82 | BRAF (0.69) | CYP1A2ALDH1A1ALOX15CYP2D6KDR | |
| SCHEMBL13898096 | 0.81 | MAPK14 (0.52) | CYP1A2CYP3A4TSHRALDH1A1HSD17B10 | |
| SCHEMBL13897988 | 0.81 | BRAF (0.55) | CYP1A2CYP3A4TSHRALDH1A1HSD17B10 | |
| SCHEMBL1825916 | 0.81 | LCK (0.47) | CYP1A2CYP3A4TSHRALDH1A1HSD17B10 | |
| SCHEMBL3829904 | 0.81 | KDR (0.65) | MAPK14KDRTEKBRAFLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101421262-A | Compounds and compositions as protein kinase inhibitors | IRM LLC (VG) | 2009-04-29 | — | — | CN | claimed |
| US-20090069327-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-03-12 | — | — | US | claimed |
| EP-1981870-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2008-10-22 | — | — | EP | claimed |
| WO-2007092531-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2007-08-16 | — | — | WO | claimed |
| CN-101421262-A | Compounds and compositions as protein kinase inhibitors | IRM LLC (VG) | 2009-04-29 | — | — | CN | disclosed |
| US-20090069327-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069327-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | SRC, BMX, FYN | CYP1A2 4285/4885CYP3A4 4823/4885TSHR 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.