Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2829960 | 0.86 | CYP17A1 (0.56) | NAMPTKMT2ATP53NPSR1HSD17B10 | |
| SCHEMBL2477474 | 0.81 | NAMPT (0.54) | NAMPTCYP17A1HDAC1 | |
| SCHEMBL30091856 | 0.81 | GAA (0.53) | NAMPTKMT2ARAB9AHDAC1NPC1 | |
| SCHEMBL1705479 | 0.81 | GAA (0.53) | NAMPTKMT2ARAB9AHDAC1NPC1 | |
| SCHEMBL2829176 | 0.80 | POLB (0.56) | NAMPTKMT2ATP53RAB9AHDAC1 | |
| SCHEMBL13949629 | 0.79 | MEN1 (0.54) | NAMPTKMT2ARAB9AHDAC1NPC1 | |
| SCHEMBL1066788 | 0.79 | F10 (0.53) | NAMPTKMT2ARAB9AHDAC1NPC1 | |
| SCHEMBL3662421 | 0.79 | F10 (0.53) | NAMPTKMT2ARAB9AHDAC1NPC1 | |
| SCHEMBL12772560 | 0.79 | NPC1 (0.57) | NAMPTKMT2ANPSR1RAB9AHDAC1 | |
| SCHEMBL1753893 | 0.79 | MEN1 (0.50) | NAMPTKMT2ARAB9AHDAC1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |