Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | BCL3 | P20749 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477110 | 0.92 | KDM1A (0.47) | CD274KDM1AALDH1A1BCL3POLB | |
| SCHEMBL2476095 | 0.87 | CD274 (0.47) | CD274KDM1AALDH1A1BCL3TACR2 | |
| SCHEMBL2477763 | 0.86 | POLB (0.47) | CD274KDM1AALDH1A1BCL3TACR2 | |
| SCHEMBL4392198 | 0.81 | CD274 (0.46) | CD274KDM1AALDH1A1BCL3TACR2 | |
| SCHEMBL2479143 | 0.81 | KDM1A (0.45) | CD274KDM1AALDH1A1BCL3ATM | |
| SCHEMBL11898694 | 0.81 | CD274 (0.45) | CD274KDM1AALDH1A1BCL3TACR2 | |
| SCHEMBL2477762 | 0.81 | CD274 (0.45) | CD274KDM1AALDH1A1BCL3TACR2 | |
| SCHEMBL2474232 | 0.80 | NAMPT (0.47) | CD274ALDH1A1BCL3POLBLMNA | |
| SCHEMBL2477555 | 0.79 | CD274 (0.47) | CD274ALDH1A1TACR2KMT2ALMNA | |
| SCHEMBL2477400 | 0.79 | CYP2D6 (0.48) | CD274KDM1AALDH1A1BCL3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |